Clindacin 150 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Clindamycin |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Brand Name
- Clindacin
Therapeutic Class
Macrolides
Indications
- Upper respiratory infections
- Lower respiratory infections
- Skin and soft tissue infections
- Bone and joint infections
- Pelvic infections
- Intra-abdominal infections
- Septicemia and endocarditis
- Dental infections
Description
Clindacin is a lincosamide antibiotic used in the treatment of infections caused by susceptible microorganisms. Clindacin is a semisynthetic antibiotic derived from lincomycin.
Antibiotic Type
Lincosamide
Active Ingredient
Clindamycin
Aerobic Gram-positive Bacteria Susceptibility
- Staphylococcus aureus
- Staphylococcus epidermidis
- Streptococci
- Pneumococci
Anaerobic Gram-negative Bacilli Susceptibility
- Bacteroides species
- Fusobacterium species
Anaerobic Gram-positive Non-spore Forming Bacilli Susceptibility
- Propionibacterium species
- Eubacterium species
- Actinomyces species
Anaerobic and Microaerophilic Gram-positive Cocci Susceptibility
- Peptococcus species
- Peptostreptococcus species
- Microaerophilic streptococci
- C. perferinges
Dosage Forms
- Capsules
- Powder for oral solution
- IV/IM Injection
Dosage & Administration
- Clindamycin Capsule:
- 150 mg-300 mg every six hours for serious infections
- 300 mg-450 mg every six hours for more severe infections
- Clindamycin Powder for Oral Solution:
- 8-12 mg/kg/day divided into 3 or 4 equal doses for serious infections
- 13-16 mg/kg/day divided into 3 or 4 equal doses for severe infections
- 17-25 mg/kg/day divided into 3 or 4 equal doses for more severe infections
- Clindamycin IV/IM Injection:
- 600-1200 mg/day in 2- 4 equal doses for serious infections in adults
- 1200-2700 mg/day in 2-4 equal doses for more severe infections in adults
- 15 to 20 mg/kg/day in 3 to 4 equal doses for neonates
Interactions
- Enhances the action of other neuromuscular blocking agents
- Antagonism with erythromycin
Contraindications
Patients previously found to be sensitive to clindamycin or any of the ingredients of this medicine
Side Effects
- Abdominal pain
- Oesophagitis and oesophageal ulcer
- Nausea
- Vomiting
- Diarrhea
- Pruritus
- Skin rashes
- Urticaria
Pregnancy & Lactation
Pregnancy Category B. Clindamycin crosses the placenta in humans. Clindamycin should be used in pregnancy only if clearly needed. Clindamycin has been reported to appear in breast milk. Therefore, it is not recommended for nursing mothers if not clearly needed.
Precautions & Warnings
Prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis
Use in Special Populations
Appropriate monitoring of organ system functions is desirable for newborns and infants
Adult Dose Adjustment
Dose adjustment of Clindacin is not necessary for geriatric use
Overdose Effects
Overdosage with orally administered Clindacin has been rare. Haemodialysis and peritoneal dialysis are not effective in removing Clindacin from the serum.
Reconstitution
Direction for reconstitution of powder for oral solution and dilution of injection for intravenous use provided
Storage Conditions
Below 30°C, away from light and moisture