Asiclin 150 mg (Capsule)

Unit Price: ৳ 8.00 (30's pack: ৳ 240.00)

Medicine Details

Category Details
Generic Clindamycin
Company Asiatic laboratories ltd
Also available as
Asiclin 300 mg capsule

Indications

  • Upper respiratory infections
  • Lower respiratory infections
  • Skin and soft tissue infections
  • Bone and joint infections
  • Pelvic infections
  • Intra-abdominal infections
  • Septicemia and endocarditis
  • Dental infections
  • Multi-drug resistant Plasmodium falciporum infection

Description

  • Lincosamide antibiotic
  • Semisynthetic antibiotic derived from lincomycin
  • Effective against aerobic gram-positive cocci
  • Effective against anaerobic gram-negative bacilli
  • Effective against anaerobic gram-positive non-spore forming bacilli
  • Effective against anaerobic and microaerophilic gram-positive cocci

Dosage & Administration

  • Dosage of Clindamycin Capsule: 150 mg-300 mg every six hours for serious infections
  • Dosage of Clindamycin Powder for oral solution: 8-25 mg/kg/day divided into 3 or 4 equal doses for different infection severities
  • Dosage of Clindamycin IV/IM Injection for adults and special populations
  • Avoiding oesophageal irritation by taking capsules with a full glass of water

Interaction

  • Enhances action of neuromuscular blocking agents
  • Antagonism with erythromycin in vitro
  • Caution with concurrent administration of neuromuscular blocking agents

Contraindications

  • Contraindicated in patients sensitive to clindamycin or its ingredients

Side Effects

  • Abdominal pain
  • Oesophagitis and oesophageal ulcer
  • Nausea
  • Vomiting
  • Diarrhoea
  • Pruritus
  • Skin rashes
  • Urticaria

Pregnancy & Lactation

  • Pregnancy Category B
  • Crosses the placenta, appears in breast milk
  • Use in pregnancy only if clearly needed
  • Not recommended for nursing mothers if not clearly needed

Precautions & Warnings

  • Prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis

Use in Special Populations

  • Appropriate monitoring in newborns and infants
  • No dose adjustment needed for geriatric use

Overdose Effects

  • Rarity of overdosage with orally administered clindamycin
  • Adverse reactions similar to normal doses expected
  • Haemodialysis and peritoneal dialysis not effective in removing clindamycin from serum
  • Treatment with simple gastric lavage
  • No specific antidote known

Therapeutic Class

  • Belongs to the macrolides class

Reconstitution

  • Directions for reconstitution of powder for oral solution
  • Direction for dilution of Asiclin injection for intravenous use
  • Physico-Chemical Stability of diluted solutions of Clindacin Injection

Storage Conditions

  • Keep below 30°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

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