Cleomycin 300 mg (Capsule)

Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)
Strip Price: ৳ 150.00

Medicine Details

Category Details
Generic Clindamycin
Company Rangs pharmaceuticals ltd

Indications

  • Upper respiratory infections
  • Lower respiratory infections
  • Skin and soft tissue infections
  • Bone and joint infections
  • Pelvic infections
  • Intra-abdominal infections
  • Septicemia
  • Endocarditis
  • Dental infections
  • Multi-drug resistant Plasmodium falciporum infection

Description

  • Lincosamide antibiotic
  • Derived from lincomycin
  • Effective against aerobic gram-positive cocci
  • Effective against anaerobic gram-negative bacilli
  • Effective against anaerobic gram-positive non-spore forming bacilli
  • Effective against anaerobic and microaerophilic gram-positive cocci

Dosage & Administration

  • Dosage for serious infections: 150 mg-300 mg every six hours
  • Dosage for more severe infections: 300 mg-450 mg every six hours
  • Dosage for bone & joint infections: 300 mg capsule 3-4 times daily
  • Pediatric dosage: 8-25 mg/kg/day divided into 3 or 4 equal doses
  • Dosage for adults with serious infections: 600-1200 mg/day in 2-4 equal doses
  • Dosage for more severe infections in adults: 1200-2700 mg/day in 2-4 equal doses

Interaction

  • Enhances the action of other neuromuscular blocking agents
  • Antagonism with erythromycin

Contraindications

  • Patients sensitive to clindamycin or any of the ingredients

Side Effects

  • Abdominal pain
  • Oesophagitis and oesophageal ulcer
  • Nausea
  • Vomiting
  • Diarrhoea
  • Pruritus
  • Skin rashes
  • Urticaria

Pregnancy & Lactation

  • Category B for pregnancy
  • Crosses the placenta
  • Appears in breast milk

Precautions & Warnings

  • Prescribed with caution in individuals with a history of gastrointestinal disease

Use in Special Populations

  • Appropriate monitoring in newborns and infants
  • No dose adjustment necessary for geriatric use

Overdose Effects

  • Rare overdosage with similar adverse reactions
  • Haemodialysis and peritoneal dialysis not effective
  • Treated with simple gastric lavage

Therapeutic Class

  • Macrolides

Reconstitution

  • Direction for reconstitution of powder for oral solution
  • Dilution of injection for intravenous use
  • Physico-chemical stability of diluted solutions
  • Reconstituted solution should be used within 2 weeks if kept at room temperature

Storage Conditions

  • Keep below 30°C
  • Away from light & moisture
  • Keep out of the reach of children

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