Endamycin 300 mg (Capsule)

Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)
Strip Price: ৳ 150.00

Medicine Details

Category Details
Generic Clindamycin
Company Euro pharma ltd
Also available as
Endamycin 150 mg capsule

Indications

  • Treatment of upper respiratory infections
  • Treatment of lower respiratory infections
  • Treatment of skin and soft tissue infections
  • Treatment of bone and joint infections
  • Treatment of pelvic infections
  • Treatment of intra-abdominal infections
  • Treatment of septicemia and endocarditis
  • Treatment of dental infections
  • Alternative therapy for multi-drug resistant Plasmodium falciporum infection

Description

  • Lincosamide antibiotic
  • Derived from lincomycin
  • Effective against aerobic gram-positive cocci
  • Effective against anaerobic gram-negative bacilli
  • Effective against anaerobic gram-positive non-spore forming bacilli
  • Effective against anaerobic and microaerophilic gram-positive cocci

Dosage & Administration

  • Serious Infections: 150 mg-300 mg every six hours
  • More severe infections: 300 mg-450 mg every six hours
  • Dosage range for serious infections: 8-12 mg/kg/day divided into 3 or 4 equal doses
  • Dosage range for severe infections: 13-16 mg/kg/day divided into 3 or 4 equal doses
  • Dosage range for more severe infections: 17-25 mg/kg/day divided into 3 or 4 equal doses
  • Adult dosage for serious infections: 600-1200 mg/day in 2-4 equal doses
  • Adult dosage for more severe infections: 1200-2700 mg/day in 2-4 equal doses
  • Dosage for neonates: 15 to 20 mg/kg/day in 3 to 4 equal doses
  • Dosage for pediatric patients: 20 to 40 mg/kg/day in 3 or 4 equal doses

Interaction

  • Endamycin enhances the action of other neuromuscular blocking agents
  • Antagonism with erythromycin demonstrated in vitro

Contraindications

  • Contraindicated in patients sensitive to clindamycin or any ingredients of the medicine

Side Effects

  • Abdominal pain
  • Oesophagitis and oesophageal ulcer
  • Nausea
  • Vomiting
  • Diarrhoea
  • Pruritus
  • Skin rashes
  • Urticaria

Pregnancy & Lactation

  • Pregnancy Category B
  • Crosses the placenta in humans
  • Should be used in pregnancy only if clearly needed
  • Reported to appear in breast milk
  • Not recommended for nursing mothers if not clearly needed

Precautions & Warnings

  • Prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis

Use in Special Populations

  • Appropriate monitoring of organ system functions desirable for newborns and infants
  • No dose adjustment necessary for geriatric use

Overdose Effects

  • Rare with orally administered Endamycin
  • Haemodialysis and peritoneal dialysis not effective in removing Endamycin from the serum
  • Treated with simple gastric lavage
  • No specific antidote known

Therapeutic Class

  • Macrolides

Reconstitution

  • Direction for reconstitution of powder for oral solution
  • Dilution of Endamycin injection for intravenous use
  • Physico-chemical stability of diluted solutions of Clindacin Injection

Storage Conditions

  • Keep below 30°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

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