Chloramphenicol 250 mg (Capsule)
Unit Price: ৳ 2.20 (100's pack: ৳ 220.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Chloramphenicol oral |
| Company | Hudson pharmaceuticals ltd |
Indications
- Treatment of serious infections
- Use in organisms susceptible to its effects
- Initiating antibiotic therapy
- In vitro sensitivity testing
Pharmacology
- Exerts mainly bacteriostatic effect
- Active against a wide range of bacteria
- Particularly active against Salmonella typhi and Haemophilus influenzae
- Interferes with protein synthesis
- Rapid absorption from GI tract
- Excretion in urine and feces
- Non-uniform distribution in the body
Dosage & Administration
- Recommended doses for therapeutic activity
- Serum concentration of 5 to 20 mcg/ml
- Dosing in adults and pediatric patients
- Dosing in patients with hepatic or renal impairment
Interaction
- Retards biotransformation of certain drugs
- Competitive inhibition with erythromycin, lincomycin, and clindamycin
- Reduced concentrations with rifampin therapy
Contraindications
- Hypersensitivity or toxic reaction to the product
- Not for trivial infections or non-indicated uses
Precautions & Warnings
- Monitoring of hematologic functions
- Early detection of hematologic changes
Overdose Effects
- Toxic effects at levels exceeding 25 mcg/ml
- Aplastic anemia, thrombocytopenia, leukopenia
- Nausea, vomiting, and diarrhea
- Use of charcoal hemoperfusion
Therapeutic Class
- Macrolides
Storage Conditions
- Store in a cool dry place
- Keep bottle securely closed
- Protect from light