Cloram 0.5% (Ophthalmic Solution)

Indications

• Treatment of ocular infections involving the conjunctiva and/or cornea
• Caused by Cloram-susceptible organisms
• Infections caused by Staphylococcus aureus, Streptococcus pneumoniae, E.coli, H. influenzae, Klebsiella/Enterobacter spp, Moraxella lacunata, and Neisseria species

Pharmacology

• Broad-spectrum bacteriostatic antibiotic
• Inhibition of bacterial protein synthesis
• Interference with the transfer of activated amino acids

Dosage & Administration

• Instill 1 or 2 drops in the conjunctival sac 4-6 times per day for the first 72 hours
• Then every 4 hours thereafter
• Treatment duration approximately 7 days
• Not to be continued for more than 3 weeks without re-evaluation by the physician

Interaction

• Inhibition of chymotrypsin if given simultaneously with Cloram

Contraindications

• History of hypersensitivity to Chloramphenicol
• Hypersensitivity to any ingredients of the preparation

Side Effects

• Burning
• Stinging
• Conjunctival hyperemia
• Blood dyscrasia
• Allergic or inflammatory reactions
• Vesicular and maculopapular dermatitis

Pregnancy & Lactation

• Use only when considered essential by the physicians
• Safety not established

Precautions & Warnings

• Never given for minor infections or prophylaxis
• Repeated course and prolonged treatment should be avoided
• Possible occurrence of blood dyscrasias
• Granulocytopenia, thrombocytopenia, and moderate anemia

Overdose Effects

• Low toxicity due to low content of antibiotic
• Unlikely toxicity from accidental ingestion

Therapeutic Class

• Ear Anti-Infectives & Antiseptics
• Eye Anti-Infectives & Antiseptics
• Macrolides

Storage Conditions

• Store in a cool place (between 2°C-8°C)
• Store in a dry place
• Protect from light
• Keep out of reach of children
• Do not touch the dropper tip to the surface
• Do not use after 30 days of the first opening

Related Brands

• A-Phenicol 0.5% (Ophthalmic Solution) - acme-laboratories-ltd