G-Chloramphenicol 0.5% (Ophthalmic Solution)
10 ml drop: ৳ 20.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Chloramphenicol ophthalmic |
| Company | Gonoshasthaya pharma ltd |
Indications
- Treatment of ocular infections involving the conjunctiva and/or cornea
- Caused by G-G-Chloramphenicol-susceptible organisms
- Such as Staphylococcus aureus, Streptococcus pneumoniae, E.coli, H. influenzae, Klebsiella/Enterobacter spp, Moraxella lacunata, and Neisseria species
Pharmacology
- Broad-spectrum bacteriostatic antibiotic
- Inhibition of bacterial protein synthesis
- Interference with the transfer of activated amino acids from soluble RNA to ribosomes
Dosage & Administration
- Instill 1 or 2 drops in the conjunctival sac 4-6 times per day for the first 72 hours
- Then every 4 hours thereafter
- Treatment should be continued for approximately 7 days
- Not to be continued for more than 3 weeks without re-evaluation by the physician
Interaction
- Inhibition of Chymotrypsin if given simultaneously with G-G-Chloramphenicol
Contraindications
- Individuals with a history of hypersensitivity to Chloramphenicol or any ingredients of the preparation
Side Effects
- Burning
- Stinging
- Conjunctival hyperemia
- Blood dyscrasia
- Allergic or inflammatory reactions
- Vesicular and maculopapular dermatitis
Pregnancy & Lactation
- Safety for use in pregnancy and lactation has not been established
- Use only when considered essential by the physicians
Precautions & Warnings
- Never be given for minor infections or for prophylaxis
- Repeated course and prolonged treatment should be avoided
- Blood dyscrasias may occur after prolonged ophthalmic use
Overdose Effects
- Accidental ingestion unlikely to cause toxicity due to low content of antibiotic
Therapeutic Class
- Ear Anti-Infectives & Antiseptics
- Eye Anti-Infectives & Antiseptics
- Macrolides
Storage Conditions
- Store in a cool and dry place (between 2°C-8°C)
- Protect from light
- Keep out of reach of children
- Do not touch the dropper tip to the surface
- Do not use after 30 days of the first opening