I-Guard 0.5% (Ophthalmic Solution)

10 ml drop: ৳ 34.40

Medicine Details

Category Details
Generic Chloramphenicol ophthalmic
Company Incepta pharmaceuticals ltd

Indications

  • Treatment of ocular infections involving the conjunctiva and/or cornea
  • Effective against Staphylococcus aureus, Streptococcus pneumoniae, E.coli, H. influenzae, Klebsiella/Enterobacter spp, Moraxella lacunata, and Neisseria species

Pharmacology

  • Chloramphenicol as a broad-spectrum bacteriostatic antibiotic
  • Inhibition of bacterial protein synthesis by interfering with the transfer of activated amino acids from soluble RNA to ribosomes

Dosage & Administration

  • Instill 1 or 2 drops in the conjunctival sac 4-6 times per day for the first 72 hours
  • Maintenance dose of every 4 hours thereafter
  • Treatment duration of approximately 7 days
  • Maximum treatment duration of 3 weeks without re-evaluation by the physician

Interaction

  • Inhibition of chymotrypsin if given simultaneously with I-Guard

Contraindications

  • Contraindicated in individuals with a history of hypersensitivity to Chloramphenicol or any ingredients of the preparation

Side Effects

  • Frequently reported adverse reactions include burning, stinging, conjunctival hyperemia, blood dyscrasia, allergic or inflammatory reactions, vesicular and maculopapular dermatitis

Pregnancy & Lactation

  • Safety for use in pregnancy and lactation has not been established
  • Use only when considered essential by the physicians

Precautions & Warnings

  • Avoid giving for minor infections or prophylaxis
  • Refrain from repeated course and prolonged treatment
  • Blood dyscrasias (granulocytopenia, thrombocytopenia, and moderate anemia) may occur after prolonged ophthalmic use

Overdose Effects

  • Accidental ingestion is unlikely to cause any toxicity due to low antibiotic content

Therapeutic Class

  • Ear Anti-Infectives & Antiseptics
  • Eye Anti-Infectives & Antiseptics
  • Macrolides

Storage Conditions

  • Store in a cool (between 2°C-8°C) and dry place
  • Protect from light
  • Keep out of reach of children
  • Do not touch the dropper tip to the surface to avoid contamination
  • Do not use after 30 days of the first opening

Related Brands