Arlin 100 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 280.00

Medicine Details

Category Details
Generic Linezolid
Company Beximco pharmaceuticals ltd
Also available as
Arlin 600 mg tablet Arlin 400 mg tablet Arlin 2 mg injection

Title

  • Arlin
  • Linezolid Tablets and IV Infusion

Categories

  • Antibacterial Medication
  • Medication for Pneumonia
  • Skin and Skin Structure Infection Treatment

Description

  • Effective against Nosocomial Pneumonia
  • Treats Community-acquired Pneumonia
  • Combat skin and skin structure infections
  • Inhibits vancomycin-resistant Enterococcus faecium

Color Options

  • White tablets

Dosage Forms

  • Tablet
  • Intravenous Infusion

Usage

  • Oral administration with or without food
  • Intravenous infusion over 30 to 120 minutes

Dosage

  • Pediatric: 10 mg/kg every 8 hours
  • Adults and Adolescents: 600 mg every 12 hours

Recommended Duration of Treatment

  • 10 to 14 days for nosocomial pneumonia
  • 14 to 28 days for complicated skin and skin structure infections

Pharmacology

  • Inhibits bacterial protein synthesis
  • Bacteriostatic against enterococci and staphylococci

Contraindications

  • Hypersensitivity to Linezolid
  • Use with monoamine oxidase inhibitors
  • Uncontrolled hypertension

Side Effects

  • Diarrhea
  • Headache
  • Nausea
  • Hypertension

Pregnancy & Lactation

  • Consideration for use during pregnancy
  • Presence in breast milk

Precautions & Warnings

  • Monitoring of complete blood counts
  • Ophthalmic evaluation for visual impairment symptoms
  • Not approved for catheter-related infections

Overdose Effects

  • No reported cases
  • Symptomatic and supportive care advised

Therapeutic Class

  • Macrolides

Reconstitution

  • Oral suspension reconstitution process
  • Intravenous infusion administration

Storage Conditions

  • Room temperature (15°C-30°C)
  • Protection from light and moisture

Interaction - Medication

  • Potential interaction with adrenergic and serotonergic agents

Interaction - Food and Others

  • Advice to avoid foods or beverages with high tyramine content

Dosage Adjustment

  • No dose adjustment needed when switching routes of administration

Intravenous Administration

  • Visual inspection against light source for particulate matter
  • Yellow coloration over time without loss of potency

Hepatic Impairment

  • No dose adjustment for mild-to-moderate impairment

Pediatric Use

  • Description of dosing regimen for neonates and children

Use in CNS Infections

  • Not recommended for empiric treatment

Precautions for Hypertension

  • Avoid in uncontrolled hypertension
  • Monitor for potential increases in blood pressure

CDAD

  • History required due to reported occurrences

Severe Hepatic Impairment

  • Pharmacokinetics not evaluated in this population

Recalled Symptoms

  • Nausea
  • Vomiting
  • Acidosis
  • Low bicarbonate level

Hyoglycemia

  • Potential need for insulin dose adjustment or discontinuation

Adverse Event Intensity

  • Mostly reported as mild to moderate

Vision Impairment

  • Recommendation for ophthalmic evaluation

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