Linexil 100 mg/5 ml (Powder for Suspension)
100 ml bottle: ৳ 280.85
Medicine Details
| Category | Details |
|---|---|
| Generic | Linezolid |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Nosocomial pneumonia
- Community-acquired pneumonia
- Complicated skin and skin structure infection including diabetic foot infections, without concomitant osteomyelitis
- Uncomplicated skin and skin structure infections
- Vancomycin-resistant Enterococcus faecium infections
Pharmacology
- Synthetic antibacterial agent
- Oxazolidinones class of antibiotics
- In vitro activity against Gram positive aerobic bacteria
- Inhibits bacterial protein synthesis
- Bacteriostatic against enterococci and staphylococci
Dosage & Administration
- Infection:
- Nosocomial pneumonia
- Community-acquired pneumonia
- Complicated skin and skin structure infections
- Uncomplicated skin and skin structure infections
- Dosage, route, and frequency:
- Pediatric patients: 10 mg/kg orally or intravenously every 8 hours
- Adults and adolescent: 600 mg orally or intravenously every 12 hours
- Recommended duration of treatment (consecutive days): 10 to 14
- Intravenous administration: 30 to 120 minutes
- Hepatic impairment: No dose adjustment for mild-to-moderate impairment
Interaction
- Drug interaction with medication: Reversible, nonselective inhibitor of monoamine oxidase
- Drug interaction with food and others: Avoid large quantities of foods or beverages with high tyramine content
Contraindications
- Known hypersensitivity to Linezolid or any of the other product components
- Concomitant use with MAO inhibitors or within two weeks of such use
- Uncontrolled hypertension, pheochromocytoma, thyrotoxicosis
Side Effects
- Diarrhea
- Headache
- Nausea
- Hypertension
- Dyspepsia
- Localized abdominal pain
- Pruritus
- Tongue discoloration
Pregnancy & Lactation
- Pregnancy: Use only if potential benefit justifies potential risk to the fetus
- Lactation: Consider developmental and health benefits of breastfeeding
Precautions & Warnings
- Monitor complete blood counts weekly
- Prompt ophthalmic evaluation for symptoms of visual impairment
- Avoid treatment for catheter-related bloodstream infections
- Monitor for potential increases in blood pressure
- Immediate medical evaluation for certain symptoms
Overdose Effects
Symptomatic and supportive care advised
Therapeutic Class
Macrolides
Reconstitution
- Oral Suspension: Reconstitute with boiled and cooled water
- Intravenous Administration: Administer by intravenous infusion over 30 to 120 minutes
Storage Conditions
Store at room temperature away from light and moisture