Rifaxin 200 mg (Tablet)
Unit Price: ৳ 20.00 (3 x 8: ৳ 480.00)
Strip Price: ৳ 160.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rifaximin |
| Company | Ziska pharmaceuticals ltd |
| Also available as |
Title
- Rifaxin
Categories
- Antibiotic
- Gastrointestinal Health
- Traveler's Health
Description
- Rifaxin is indicated for the treatment of traveler's diarrhea by noninvasive strains of E. coli, reduction in risk of overt hepatic encephalopathy, and bacterial overgrowth of irritable bowel syndrome. It is a semisynthetic, rifamycin-based non-systemic antibiotic that inhibits bacterial RNA synthesis by its action on the beta-subunit of the DNA-dependent RNA polymerase.
Dimensions
- N/A
Color options
- N/A
Functions
- Treatment of traveler's diarrhea
- Reduction in risk of overt hepatic encephalopathy
- Bacterial overgrowth of irritable bowel syndrome
- Inhibition of bacterial RNA synthesis
Materials
- Rifamycin-based non-systemic antibiotic
Technical specifications
- Very little of the drug will pass the gastrointestinal wall into the circulation
- Broad spectrum activity against Gram-positive and Gram-negative bacteria
- Bactericidal action against many species of bacteria
Design elements
- Semisynthetic
- Non-systemic antibiotic
Usability features
- Can be taken with or without food
Dosage
- For Traveler's Diarrhea: 200 mg 3 times daily for 3 days (patients ≥12 years of age)
- For Hepatic Encephalopathy: 550 mg 2 times daily (patients ≥18 years of age)
- For Bacterial overgrowth of irritable bowel syndrome: 400 mg 3 times daily for 10 days or 550 mg 3 times daily for 14 days
Interaction
- In vitro study suggests induction of CYP3A4 by Rifaxin
- Not expected to induce CYP3A4 in patients with normal liver function
Contraindications
- Hypersensitivity to Rifaximin or any rifamycin antimicrobial agents or any components of the product
Side effects
- Flatulence
- Headache
- Abdominal pain
- Rectal tenesmus
- Defecation urgency
- Nausea
- Constipation
- Pyrexia
- Vomiting
- Anaphylaxis
- Angioneurotic edema
- Exfoliative dermatitis
Pregnancy lactation
- Pregnancy category C
- Not known whether excreted in human milk
Precautions warnings
- Not effective in patients with diarrhea complicated by fever and/or blood in the stools
- Discontinue if diarrhea symptoms worsen or persist for more than 24-48 hours
- Consider alternative antibiotic therapy if needed
- Risk of pseudomembranous colitis with antibacterial agents
- Consider diagnosis in patients with diarrhea after antibacterial administration
Use special populations
- Renal Impairment: Pharmacokinetics not studied
- Hepatic Impairment: Markedly elevated systemic exposure in patients with hepatic impairment
Overdose effects
- No specific information available on treatment of overdose
- Discontinue Rifaxin, treat symptomatically, and institute supportive measures as required
Therapeutic class
- 4-Quinolone preparations
Storage conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children