Aximin 550 mg (Tablet)
Unit Price: ৳ 45.13 (1 x 10: ৳ 451.30)
Strip Price: ৳ 451.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Rifaximin |
| Company | Acme laboratories ltd |
| Also available as |
Title
- Aximin
Categories
- Antibiotic
- Medication
- Therapeutic
Description
- Aximin is indicated for the treatment of traveler's diarrhea by noninvasive strains of E. coli, reduction in risk of overt hepatic encephalopathy, and bacterial overgrowth of irritable bowel syndrome. It is a rifamycin-based non-systemic antibiotic that inhibits bacterial RNA synthesis by its action on the beta-subunit of the DNA-dependent RNA polymerase.
Dosage and Administration
- For traveler's diarrhea in patients ≥12 years of age: 200 mg 3 times daily for 3 days
- For hepatic encephalopathy in patients ≥18 years of age: 550 mg 2 times daily
- For bacterial overgrowth of irritable bowel syndrome: 400 mg 3 times daily for 10 days or 550 mg 3 times daily for 14 days. Can be taken with or without food
Interaction
- In vitro study suggests that Aximin induces CYP3A4, but in patients with normal liver function, Aximin at the recommended dosing regimen is not expected to induce CYP3A4.
Contraindications
- Hypersensitivity to Rifaximin or to any of the rifamycin antimicrobial agents, or any components of this product
Side Effects
- Flatulence
- Headache
- Abdominal pain
- Rectal tenesmus
- Defecation urgency
- Nausea
- Constipation
- Pyrexia
- Vomiting
- Reactions including anaphylaxis, angioneurotic edema, and exfoliative dermatitis
Pregnancy and Lactation
- Pregnancy category C. It is not known whether Rifaximin is excreted in human milk.
Precautions and Warnings
- Not effective in patients with diarrhea complicated by fever and/or blood in the stools
- Discontinue Aximin if diarrhea symptoms worsen or persist for more than 24-48 hours
- Consider alternative antibiotic therapy
- Pseudomembranous colitis reported with nearly all antibacterial agents
- Consider diagnosis in patients with diarrhea subsequent to the administration of antibacterial agents
Use in Special Populations
- Renal impairment: The pharmacokinetics of Aximin in patients with impaired renal function have not been studied
- Hepatic Impairment: Systemic exposure of Aximin was markedly elevated in patients with hepatic impairment compared to healthy subjects
Overdose Effects
- No specific information available on the treatment of overdose with Aximin
Therapeutic Class
- 4-Quinolone preparations
Storage Conditions
- Keep below 30°C temperature, away from light & moisture
- Keep out of the reach of children