Faxan 550 mg (Tablet)
Unit Price: ৳ 45.00 (2 x 7: ৳ 630.00)
Strip Price: ৳ 315.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rifaximin |
| Company | Drug international ltd |
| Also available as |
Indications
- Treatment of traveler's diarrhea by noninvasive strains of E. coli
- Reduction in risk of overt hepatic encephalopathy
- Bacterial overgrowth of irritable bowel syndrome
Pharmacology
- Rifaximin is a semisynthetic, rifamycin-based non-systemic antibiotic
- Inhibits bacterial RNA synthesis by its action on the beta-subunit of the DNA-dependent RNA polymerase
- Broad spectrum activity against many species of bacteria
Dosage & Administration
- 200 mg 3 times daily for 3 days for traveler's diarrhea in patients ≥12 years of age
- 550 mg 2 times daily for hepatic encephalopathy in patients ≥18 years of age
- 400 mg 3 times daily for 10 days or 550 mg 3 times daily for 14 days for bacterial overgrowth of irritable bowel syndrome
Interaction
- In vitro study suggests Faxan induces CYP3A4
- Not expected to induce CYP3A4 in patients with normal liver function
Contraindications
- Hypersensitivity to Rifaximin or rifamycin antimicrobial agents
- Hypersensitivity to any components of the product
Side Effects
- Flatulence
- Headache
- Abdominal pain
- Rectal tenesmus
- Defecation urgency
- Nausea
- Constipation
- Pyrexia
- Vomiting
- Reactions including anaphylaxis, angioneurotic edema, exfoliative dermatitis
Pregnancy & Lactation
- Pregnancy Category C
- Excretion in human milk unknown
Precautions & Warnings
- Not effective in patients with diarrhea complicated by fever and/or blood in the stools
- Discontinue therapy if symptoms worsen or persist for more than 24-48 hours
- Consider pseudomembranous colitis diagnosis in patients with diarrhea after antibiotic administration
Use in Special Populations
- Renal impairment data not studied
- Markedly elevated systemic exposure in patients with hepatic impairment
Overdose Effects
- No specific information available
- Discontinue Faxan, treat symptomatically, institute supportive measures in case of overdose
Therapeutic Class
- 4-Quinolone preparations
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children