Clamox 500 mg+125 mg (Tablet)

Unit Price: ৳ 32.00 (2 x 6: ৳ 384.00)
Strip Price: ৳ 192.00

Medicine Details

Category Details
Generic Amoxicillin clavulanic acid
Company Opsonin pharma ltd
Also available as
Clamox 500 mg injection Clamox 1 gm injection Clamox 125 mg suspension Clamox 875 mg tablet Clamox 250 mg tablet Clamox ds 400 mg suspension

Indications

  • Short-term treatment of bacterial infections
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Genito-urinary tract infections
  • Skin and soft tissue infections
  • Bone and joint infections
  • Other infections

Composition

  • 375 mg tablet
  • 625 mg tablet
  • 1 gm tablet
  • Powder for Suspension
  • Powder for Suspension (Forte)
  • 1.2 gm Injection
  • 0.6 gm injection

Pharmacology

  • Bactericidal activity
  • Broad spectrum of activity
  • Pharmacokinetics
  • Peak serum levels

Dosage

  • Tablet for adults and children over 12 years
  • Suspension for children of different age groups
  • Recommended daily dosage for mild to moderate infections
  • Recommended daily dosage for serious infections
  • IV Injection for adults and children

Administration

  • Oral dosage form
  • IV injection administration
  • Enhanced absorption when taken at the start of a meal
  • Intravenous injection and infusion instructions

Interaction

  • Prolongation of bleeding time
  • Reduced efficacy of oral contraceptives
  • Concomitant use of allopurinol
  • Data on concomitant use with allopurinol

Contraindications

  • Penicillin hypersensitivity
  • Cross-sensitivity with other beta-lactam antibiotics
  • History of Co-amoxiclav or Penicillin-associated cholestatic jaundice

Side Effects

  • Uncommon side effects
  • Diarrhea
  • Pseudomembranous colitis
  • Indigestion
  • Nausea
  • Vomiting
  • Candidiasis
  • Hepatitis
  • Cholestatic jaundice
  • Urticarial and erythematous rashes
  • Erythema multiforme
  • Stevens-Johnson Syndrome
  • Exfoliative dermatitis
  • Angioedema
  • Anaphylaxis

Pregnancy & Lactation

  • Animal studies on teratogenic effect
  • Limited use in human pregnancy
  • Detection of Amoxicillin in breast milk

Precautions & Warnings

  • Careful use in patients on anticoagulation therapy
  • Use with severe hepatic dysfunction
  • Dosage adjustment for moderate or severe renal impairment

Use in Special Populations

  • Dose adjustment for renal impairment
  • Hepatic impairment caution

Overdose Effects

  • Unlikelihood of overdose
  • Possible gastrointestinal symptoms
  • Disturbance of fluid and electrolyte balances
  • Possible removal by haemodialysis

Therapeutic Class

  • Broad spectrum penicillins

Reconstitution

  • Reconstitution of IV injection
  • Incompatible reconstitution or mixing
  • Injection into the drip tubing of infusion fluids

Storage Conditions

  • Storage below 25°C
  • Protection from light and moisture
  • Refrigeration of reconstituted suspension
  • Usage within 7 days of reconstitution
  • Usage within 20 minutes of reconstitution

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