Vancard 500 mg/vial (IV Infusion)
500 mg vial: ৳ 244.78
Medicine Details
| Category | Details |
|---|---|
| Generic | Vancomycin hydrochloride |
| Company | Techno drugs ltd |
| Also available as |
Indications
- Treatment of potentially life-threatening infections
- Effective in severe staphylococcal infections
- Treatment of endocarditis
- Prophylaxis against endocarditis
- Treatment of infections due to staphylococci like osteomyelitis, pneumonia, septicemia, and soft tissue infections
Pharmacology
- Binds tightly to D-alanyl-D-alanine portion cell wall precursor
- Blocks glycopeptide polymerisation
- Inhibits cell wall synthesis
- Causes damage to the cytoplasmic membrane
Dosage & Administration
- Recommended concentrations and rates for adults
- Different dosages for patients with normal renal function and impaired renal function
- Dosage adjustment for elderly patients
- Capsule dosage for adults and pediatrics
Contraindications
- Patients with known hypersensitivity to Vancomycin
Side Effects
- Anaphylactic reactions
- Hypotension
- Wheezing
- Dyspnoea
- Urticaria
- Pruritus
- Flushing of the upper body
- Pain and muscle spasm of the chest and back
- Injection site necrosis when injected intramuscularly
- Thrombophlebitis
- Pseudomembranous colitis
Pregnancy & Lactation
- Use in pregnancy only if clearly needed
- Caution in nursing women
- Unlikely significant absorption for nursing infants
Precautions & Warnings
- Tests for auditory function in patients with borderline renal function
- Serial tests of Vancard blood levels in patients over 60
- Periodic haematological studies, urine analysis, and renal function tests
- Injection site necrosis risk when injected intramuscularly
- Superinfection risk
- Observation for overgrowth of non-susceptible organisms
- Reports of pseudomembranous colitis
Overdose Effects
- Supportive care advised
- Poor removal by haemodialysis or peritoneal dialysis
- Limited benefit from haemoperfusion with Amberlite resin XAD-4
Therapeutic Class
- Other antibiotic
Storage Conditions
- Store in cool, dry place
- Protect from light
- Keep out of reach of children