Vancomin 1 gm/vial (IV Infusion)
1 gm vial: ৳ 483.25
Medicine Details
| Category | Details |
|---|---|
| Generic | Vancomycin hydrochloride |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Treatment of potentially life-threatening infections
- Useful in severe staphylococcal infections
- Therapy for endocarditis
- Prophylaxis against endocarditis
- Treatment of infections including osteomyelitis, pneumonia, septicemia, and soft tissue infections
Pharmacology
- Binds tightly to D-alanyl-D-alanine portion cell wall precursor
- Causes blockage of glycopeptide polymerization
- Inhibition of cell wall synthesis
- Secondary damage to the cytoplasmic membrane
Dosage & Administration
- Recommended concentrations and rates for adults
- Dosage for patients with normal renal function
- Dosage for patients with impaired renal function and elderly patients
- Recommended dosage adjustments
- Recommended method of administration
Contraindications
- Hypersensitivity to Vancomycin
Side Effects
- Anaphylactic reactions
- Hypotension
- Wheezing
- Dyspnoea
- Urticaria
- Pruritus
- Flushed upper body
- Pain and muscle spasm of the chest and back
- Reaction resolution timeframe
- Infusion method impact on reactions frequency
Pregnancy & Lactation
- Unknown impact on fetal harm
- Caution in pregnancy
- Careful monitoring of blood levels
- Excretion in human milk
- Caution in nursing women
- Unlikelihood of significant absorption by nursing infants
Precautions & Warnings
- Serial tests for auditory function and blood levels for specific demographics
- Periodic hematological studies
- Urine analysis
- Irritation to tissue
- Injection site necrosis
- Necessity of intravenous infusion
- Injection site pain and thrombophlebitis prevalence
- Possible overgrowth of non-susceptible organisms
- Observation and superinfection measures
- Reports of pseudomembranous colitis in rare instances
Overdose Effects
- Supportive care advised
- Maintenance of glomerular filtration
- Poor removal from blood by haemodialysis or peritoneal dialysis
- Limited benefit of haemoperfusion with Amberlite resin XAD-4
Therapeutic Class
- Other antibiotic
Storage Conditions
- Cool and dry storage
- Protected from light
- Keep out of reach of children