Aptrim (200 mg+40 mg)/5 ml (Oral Suspension)

60 ml bottle: ৳ 20.54

Medicine Details

Category Details
Generic Sulphamethoxazole trimethoprim
Company Apollo pharmaceutical ltd
Also available as
Aptrim 800 mg tablet

ProductTitle

  • Cotrimoxazole

Categories

  • Antibiotic
  • Antimicrobial
  • Anti-Diarrheal
  • Sulphonamide
  • Trimethoprim

Description

  • Bactericidal action against a wide range of Gram-positive and Gram-negative organisms
  • Broad spectrum bactericidal activity
  • Pharmacological activity against bacteria and some protozoa
  • Dosage and administration for mild to severe infections
  • Contraindications due to hypersensitivity and specific medical conditions
  • Rare reported side effects such as crystalluria, haemolysis, and thrombocytopenia
  • Pregnancy and lactation considerations
  • Precautions for prolonged full dose treatment and diabetic patients
  • Therapeutic class as anti-diarrheal antimicrobial drugs, sulphonamides, and trimethoprim
  • Storage conditions below 30°C, away from light and moisture

Indications

  • Treatment of respiratory tract infections
  • Treatment of genito-urinary tract infections
  • Treatment of gastrointestinal tract infections
  • Treatment of other infections confirmed to be susceptible to Cotrimoxazole
  • Particularly suitable for chronic bronchitis and urinary tract infections

Pharmacology

  • Broad spectrum bactericidal activity against a wide range of bacteria and some protozoa

DosageAndAdministration

  • Double strength tablet dosage for over 12 years
  • Tablet and suspension dosages for different age groups and infection severity

Contraindications

  • Hypersensitivity to trimethoprim or sulphonamides
  • Megaloblastic anaemia due to folate deficiency
  • Marked liver parenchymal damage, blood dyscrasia, severe renal insufficiency, glucose 6-phosphate dehydrogenase deficiency

SideEffects

  • Rare side effects like crystalluria, allergic reactions, haemolysis, thrombocytopenia, neutropenia, agranulocytosis
  • Less serious side effects like malaise, headache, nausea, and vomiting

PregnancyAndLactation

  • Passage through placenta and breast milk, may cause kernicterus

PrecautionsAndWarnings

  • Risk of macrocytic anaemia with prolonged full dose treatment
  • Interference in the conversion of Folic acid into Folinic acid
  • Potential potentiation of action of sulphonylurea in diabetic patients receiving Aptrim

TherapeuticClass

  • Anti-diarrhoeal antimicrobial drugs
  • Sulphonamides
  • Trimethoprim

StorageConditions

  • Keep below 30°C, away from light and moisture, out of reach of children

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