Avlotrin (200 mg+40 mg)/5 ml (Oral Suspension)

60 ml bottle: ৳ 22.21

Medicine Details

Category	Details
Generic	Sulphamethoxazole trimethoprim
Company	Aci limited
Also available as	Avlotrin ds 800 mg tablet

Indications

Respiratory tract infections
Genito-urinary tract infections
Gastro-intestinal tract infections
Osteomyelitis
Brucellosis
Skin infections
Septicaemia
Bacillary dysentery
Cholera
Nocardiosis
Mycetoma

Pharmacology

Broad spectrum bactericidal activity
Activity against gram-positive bacteria
Activity against gram-negative bacteria
Activity against protozoa
Sequential blockade of bacterial enzyme systems

Dosage & Administration

Dosage for mild to moderate infections
Dosage for severe infections
Long term therapy dosage
Dosage for gonorrhoea
Different dosage for tablet and suspension

Contraindications

Hypersensitivity to trimethoprim or sulphonamides
Megaloblastic anaemia due to folate deficiency
Liver parenchymal damage
Blood dyscrasia
Severe renal insufficiency
Glucose 6-phosphate dehydrogenase deficiency

Side Effects

Crystalluria
Allergic reactions
Haemolysis
Thrombocytopenia
Neutropenia
Agranulocytosis
Malaise
Headache
Nausea
Vomiting

Pregnancy & Lactation

Passage of sulphonamides through placenta
Excretion in breast milk
Risk of kernicterus

Precautions & Warnings

Macrocytic anaemia risk
Interference with Folic acid conversion
Reversible with Folinic acid
Caution with diabetic patients
Potential potentiation of sulphonylurea drug

Therapeutic Class

Anti-diarrhoeal Antimicrobial drugs
Sulphonamides & Trimethoprim

Storage Conditions

Temperature below 30°C
Protection from light & moisture
Keep out of reach of children

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