Cotrazen 400 mg+80 mg (Tablet)

Unit Price: ৳ 1.40 (10 x 10: ৳ 140.00)
Strip Price: ৳ 14.00

Medicine Details

Indications

  • Respiratory tract infections
  • Genito-urinary tract infections
  • Gastro-intestinal tract infections
  • Osteomyelitis
  • Brucellosis
  • Skin infections
  • Septicaemia
  • Bacillary dysentery
  • Cholera

Pharmacology

Broad spectrum bactericidal activity

Dosage & Administration

  • Dosage for mild to moderate infections
  • Dosage for severe infections
  • Long term therapy dosage
  • Dosage for Gonorrhoea

Contraindications

  • Hypersensitivity to trimethoprim or sulphonamides
  • Megaloblastic anaemia due to folate deficiency
  • Marked liver parenchymal damage
  • Blood dyscrasia
  • Severe renal insufficiency
  • Glucose 6-phosphate dehydrogenase deficiency

Side Effects

  • Crystalluria
  • Allergic reactions
  • Haemolysis
  • Thrombocytopenia
  • Neutropenia
  • Agranulocytosis
  • Malaise
  • Headache
  • Nausea
  • Vomiting

Pregnancy & Lactation

Passes placenta and breast milk, may cause kernicterus

Precautions & Warnings

  • Risk of macrocytic anaemia
  • Interference in the conversion of Folic acid into Folinic acid
  • Reversible by giving Folinic acid
  • Possible potentiation of action of sulphonylurea in diabetic patients

Therapeutic Class

Anti-diarrhoeal Antimicrobial drugs, Sulphonamides & Trimethoprim

Storage Conditions

Keep below 30°C temperature, away from light & moisture, Keep out of the reach of children

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