Cots (200 mg+40 mg)/5 ml (Oral Suspension)

60 ml bottle: ৳ 22.14

Medicine Details

Category Details
Generic Sulphamethoxazole trimethoprim
Company Opsonin pharma ltd

Indications

  • Respiratory tract infections
  • Genito-urinary tract infections
  • Gastro-intestinal tract infections
  • Osteomyelitis
  • Brucellosis
  • Skin infections
  • Septicaemia
  • Bacillary dysentery
  • Cholera
  • Nocardiosis
  • Mycetoma

Pharmacology

  • Bactericidal activity
  • Broad spectrum
  • Gram-positive bacteria
  • Gram-negative bacteria
  • Protozoa
  • Sequential blockade of bacterial enzyme systems

Dosage & Administration

  • Double strength tablet for over 12 years old
  • Tablet for over 12 years old
  • Suspension for under 12 years old
  • Mild to moderate infections dosage
  • Severe infections dosage
  • Long term therapy dosage
  • Gonorrhoea treatment dosage

Contraindications

  • Hypersensitivity to trimethoprim or sulphonamides
  • Megaloblastic anaemia
  • Liver parenchymal damage
  • Blood dyscrasia
  • Severe renal insufficiency
  • Glucose 6-phosphate dehydrogenase deficiency

Side Effects

  • Crystalluria
  • Allergic reactions
  • Haemolysis
  • Thrombocytopenia
  • Neutropenia
  • Agranulocytosis
  • Malaise
  • Headache
  • Nausea
  • Vomiting

Pregnancy & Lactation

  • Passage of sulphonamides through placenta
  • Excretion in breast milk
  • Risk of kernicterus

Precautions & Warnings

  • Risk of macrocytic anaemia
  • Interference in Folic acid conversion
  • Reversible with Folinic acid
  • Caution with diabetic patients
  • Potentiation of sulphonylurea drugs

Therapeutic Class

  • Anti-diarrhoeal
  • Antimicrobial drugs
  • Sulphonamides
  • Trimethoprim

Storage Conditions

  • Below 30°C temperature
  • Away from light
  • Away from moisture
  • Keep out of the reach of children

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