Doctrim (200 mg+40 mg)/5 ml (Oral Suspension)

60 ml bottle: ৳ 22.00

Medicine Details

Category Details
Generic Sulphamethoxazole trimethoprim
Company Doctors chemical works ltd
Also available as
Doctrim 400 mg tablet Doctrim 800 mg tablet

Indications

  • Respiratory tract infections
  • Genito-urinary tract infections
  • Gastro-intestinal tract infections
  • Osteomyelitis
  • Brucellosis
  • Skin infections
  • Septicaemia
  • Bacillary dysentery
  • Cholera
  • Nocardiosis
  • Mycetoma

Pharmacology

  • Broad spectrum bactericidal activity
  • Activity against gram-positive bacteria
  • Activity against gram-negative bacteria
  • Activity against protozoa
  • Biosynthesis inhibition of folinic acid

Dosage & Administration

  • Recommended dosage for adults
  • Recommended dosage for children
  • Dosage for mild to moderate infections
  • Dosage for severe infections
  • Dosage for long term therapy

Contraindications

  • Hypersensitivity to trimethoprim or sulphonamides
  • Megaloblastic anaemia due to folate deficiency
  • Liver parenchymal damage
  • Blood dyscrasia
  • Severe renal insufficiency
  • Glucose 6-phosphate dehydrogenase deficiency

Side Effects

  • Crystalluria
  • Allergic reactions
  • Haemolysis
  • Thrombocytopenia
  • Neutropenia
  • Agranulocytosis
  • Malaise
  • Headache
  • Nausea
  • Vomiting

Pregnancy & Lactation

  • Excretion of sulphonamides in breast milk
  • Risk of kernicterus

Precautions & Warnings

  • Risk of macrocytic anaemia
  • Interference with the conversion of Folic acid
  • Potential interaction with sulphonylurea drugs

Therapeutic Class

  • Anti-diarrhoeal
  • Antimicrobial drugs
  • Sulphonamides
  • Trimethoprim

Storage Conditions

  • Temperature storage
  • Light sensitivity
  • Moisture sensitivity
  • Keep out of the reach of children

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