Meditrim 800 mg+160 mg (Tablet)

Unit Price: ৳ 2.60 (50's pack: ৳ 130.00)

Medicine Details

Category	Details
Generic	Sulphamethoxazole trimethoprim
Company	Medimet pharmaceuticals ltd
Also available as	Meditrim 400 mg tablet Meditrim 200 mg suspension

Title

Cotrimoxazole Double Strength Tablet

Description

Cotrimoxazole is bactericidal in vitro to a wide range of Gram-positive and Gram-negative organisms. It is indicated for respiratory, genito-urinary, and gastrointestinal tract infections, among others, and exerts its bactericidal action by the sequential blockade of two bacterial enzyme systems in the biosynthesis of Folinic acid in the micro-organisms.

Color Options

White

Functions

Bactericidal action
Treatment of respiratory tract infections
Treatment of urinary tract infections
Treatment of gastrointestinal tract infections
Sequential blockade of bacterial enzyme systems

Dosage

Double Strength Tablet:
- Over 12 years:
  - Mild to moderate infections: 1-1.5 tablets twice daily
  - Severe infections: 1.5 tablets twice daily or 2 tablets thrice daily
  - Long term therapy (>14 days): 0.5-1 tablet twice daily
  - Gonorrhoea: 2 tablets every 12 hours for two days or 2.5 tablets followed by a further dose of 2.5 tablets after 8 hours
- Under 12 years:
  - 6-12 years: 2 teaspoonful twice daily
  - 6 months-5 years: 1 teaspoonful twice daily
  - 6 weeks-6 months: 0.5 teaspoonful twice daily
Tablet:
- Over 12 years:
  - Mild to moderate infections: 2 tablets twice daily
  - Severe infections: 2 tablets thrice daily
  - Long term therapy (>14 days): 1 tablet twice daily
Suspension:
- Under 12 years:
  - 6-12 years: 2 teaspoonful twice daily
  - 6 months-5 years: 1 teaspoonful twice daily
  - 6 weeks-6 months: 0.5 teaspoonful twice daily

Indications

Respiratory tract infections
Acute and chronic bronchitis
Bronchiectasis
Lung abscess
Pneumocystis carinii pneumonitis
Sinusitis
Otitis media
Genito-urinary tract infections
Gastro-intestinal tract infections
Chronic carrier state infections
Osteomyelitis
Acute brucellosis
Skin infections
Wound infections
Septicaemia
Bacillary dysentery
Cholera
Nocardiosis
Mycetoma

Pharmacology

Broad spectrum bactericidal activity against a wide range of gram-positive & gram-negative bacteria and some protozoa.

Contraindications

Hypersensitivity to trimethoprim or sulphonamides
Megaloblastic anaemia due to folate deficiency
Marked liver parenchymal damage
Blood dyscrasia
Severe renal insufficiency
Glucose 6-phosphate dehydrogenase deficiency

Side Effects

Crystalluria
Allergic reactions
Haemolysis
Thrombocytopenia
Neutropenia
Agranulocytosis
Malaise
Headache
Nausea
Vomiting

Pregnancy & Lactation

Not recommended during pregnancy and nursing period due to potential transfer via placenta and breast milk

Precautions & Warnings

Prolonged treatment associated with macrocytic anaemia
Careful administration to diabetic patients receiving sulphonylurea drug

Therapeutic Class

Anti-diarrhoeal Antimicrobial drugs, Sulphonamides & Trimethoprim

Storage Conditions

Store below 30°C, away from light & moisture, out of the reach of children