Meditrim (200 mg+40 mg)/5 ml (Oral Suspension)

60 ml bottle: ৳ 20.00

Medicine Details

Category Details
Generic Sulphamethoxazole trimethoprim
Company Medimet pharmaceuticals ltd
Also available as
Meditrim 400 mg tablet Meditrim 800 mg tablet

Title

  • Cotrimoxazole Double Strength Tablet
  • Cotrimoxazole Tablet
  • Cotrimoxazole Suspension

Categories

  • Antibiotic
  • Anti-diarrhoeal
  • Antimicrobial
  • Sulphonamides
  • Trimethoprim

Description

  • Bactericidal in vitro to a wide range of Gram-positive and Gram-negative organisms
  • Broad spectrum bactericidal activity
  • Exerts bactericidal action by the sequential blockade of two bacterial enzyme systems
  • Passes the placenta and is excreted in breast milk
  • Associated with the risk of macrocytic anaemia
  • Storage temperature below 30°C
  • Keep away from light and moisture

Indications

  • Respiratory tract infections treatment and prophylaxis
  • Genito-urinary tract infections treatment
  • Gastro-intestinal tract infections treatment
  • Other infections treatment
  • Particularly suitable for chronic bronchitis and urinary tract infections

Pharmacology

  • Contains Trimethoprim and Sulphamethoxazole in a 1:5 combination
  • Bactericidal activity against gram-positive & gram-negative bacteria and some protozoa
  • Blocks two bacterial enzyme systems in the biosynthesis of folinic acid

Dosage & Administration

  • Dosage for different age groups and severity of infections
  • Tablet and suspension forms available
  • Specific dosages for mild to severe infections and long-term therapy

Contraindications

  • Hypersensitivity to trimethoprim or sulphonamides
  • Megaloblastic anaemia due to folate deficiency
  • Marked liver parenchymal damage
  • Blood dyscrasia
  • Severe renal insufficiency
  • Glucose 6-phosphate dehydrogenase deficiency

Side Effects

  • Crystalluria
  • Allergic reactions
  • Haemolysis
  • Thrombocytopenia
  • Neutropenia
  • Agranulocytosis
  • Malaise
  • Headache
  • Nausea
  • Vomiting
  • Transient nature of less serious side effects

Pregnancy & Lactation

  • Passes the placenta
  • Excreted in breast milk
  • May cause kernicterus

Precautions & Warnings

  • Risk of macrocytic anaemia
  • Interference with the conversion of Folic acid into Folinic acid
  • Reversal by giving Folinic acid
  • Caution when giving to diabetic patients receiving sulphonylurea drug

Therapeutic Class

  • Anti-diarrhoeal
  • Antimicrobial drugs
  • Sulphonamides
  • Trimethoprim

Storage Conditions

  • Temperature below 30°C
  • Keep away from light
  • Keep away from moisture
  • Keep out of the reach of children

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