Megatrim DS 800 mg+160 mg (Tablet)

Unit Price: ৳ 2.65 (15 x 10: ৳ 398.20)
Strip Price: ৳ 26.55

Medicine Details

Category Details
Generic Sulphamethoxazole trimethoprim
Company Beximco pharmaceuticals ltd
Also available as
Megatrim 200 mg suspension

Indications

  • Respiratory tract infections
  • Genito-urinary tract infections
  • Gastro-intestinal tract infections
  • Osteomyelitis
  • Brucellosis
  • Skin infections
  • Septicaemia
  • Bacillary dysentery
  • Cholera
  • Nocardiosis
  • Mycetoma

Pharmacology

  • Broad spectrum bactericidal activity
  • Biosynthesis inhibition of folinic acid
  • Activity against gram-positive bacteria
  • Activity against gram-negative bacteria
  • Activity against protozoa

Dosage & Administration

  • Recommended dosage for mild to moderate infections
  • Recommended dosage for severe infections
  • Recommended dosage for long-term therapy
  • Dosage for gonorrhoea
  • Dosage for different age groups (tablet/suspension)

Contraindications

  • Hypersensitivity to trimethoprim or sulphonamides
  • Megaloblastic anaemia due to folate deficiency
  • Liver parenchymal damage
  • Blood dyscrasia
  • Severe renal insufficiency
  • Glucose 6-phosphate dehydrogenase deficiency

Side Effects

  • Crystalluria
  • Allergic reactions
  • Haemolysis
  • Thrombocytopenia
  • Neutropenia
  • Agranulocytosis
  • Malaise
  • Headache
  • Nausea
  • Vomiting

Pregnancy & Lactation

  • Passage of sulphonamides through placenta
  • Excretion in breast milk
  • Risk of kernicterus

Precautions & Warnings

  • Risk of macrocytic anaemia
  • Interference in Folic acid conversion
  • Reversal by Folinic acid
  • Care with diabetic patients
  • Potential action potentiation with sulphonylurea drug

Therapeutic Class

  • Anti-diarrhoeal Antimicrobial drugs
  • Sulphonamides & Trimethoprim

Storage Conditions

  • Temperature below 30°C
  • Protection from light & moisture
  • Keep out of reach of children

Related Brands