Politrim 400 mg+80 mg (Tablet)

Unit Price: ৳ 1.43 (10 x 10: ৳ 143.00)

Strip Price: ৳ 14.30

Medicine Details

Category	Details
Generic	Sulphamethoxazole trimethoprim
Company	Acme laboratories ltd
Also available as	Politrim ds 800 mg tablet Politrim 200 mg suspension

Title

Cotrimoxazole Double Strength Tablet

Categories

Antimicrobial Drugs
Sulphonamides & Trimethoprim

Description

Broad spectrum bactericidal activity
Treatment of respiratory, genitourinary, gastrointestinal, and skin infections
Exerts bactericidal action by blocking bacterial enzyme systems
Dosage instructions for different age groups
Contraindications, side effects, precautions, and warnings provided
Storage conditions below 30°C

Size

Tablet

Strength

Double Strength

Main Ingredients

Trimethoprim
Sulphamethoxazole

Formulation

Tablet
Suspension

Age Group

Over 12 years
Under 12 years

Recommended Use

Mild to moderate infections
Severe infections
Long term therapy
Gonorrhea

Indications

Respiratory tract infections
Genitourinary tract infections
Gastrointestinal tract infections
Skin infections
Septicemia
Cholera
Osteomyelitis
Brucellosis
Nocardiosis
Mycetoma

Contraindications

Hypersensitivity to trimethoprim or sulphonamides
Megaloblastic anaemia due to folate deficiency
Liver parenchymal damage
Blood dyscrasia
Severe renal insufficiency
Glucose 6-phosphate dehydrogenase deficiency

Side Effects

Crystalluria
Allergic reactions
Haemolysis
Thrombocytopenia
Neutropenia
Agranulocytosis
Malaise
Headache
Nausea
Vomiting

Precautions

Risk of macrocytic anaemia
Interference in Folic acid metabolism
Reversal with Folinic acid
Monitor diabetic patients on sulphonylurea
Potentiation of sulphonylurea action

Pregnancy & Lactation

Excreted in breast milk
May cause kernicterus

Storage Conditions

Temperature below 30°C
Away from light
Away from moisture
Keep out of reach of children

Technical Specifications

Bactericidal potency against Gram-positive and Gram-negative organisms
Synergy in enzyme blockade for high bactericidal activity
Broad spectrum activity against bacteria and some protozoa

Pharmacology

Broad spectrum bactericidal activity
Sequential blockade of bacterial enzyme systems

Dosage & Administration

Specific dosages for different levels of infection severity
Dosage variations for different age groups

Warnings

Long-term use risk of macrocytic anaemia
Potential interaction with sulphonylurea in diabetic patients

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