Seematrin (200 mg+40 mg)/5 ml (Oral Suspension)

60 ml bottle: ৳ 24.00

Medicine Details

Type of Medicine

  • Antibacterial
  • Antimicrobial
  • Anti-diarrheal

Mode of Action

  • Bactericidal activity against gram-positive bacteria
  • Bactericidal activity against gram-negative bacteria
  • Sequential blockade of bacterial enzyme systems
  • Biosynthesis of folinic acid inhibition

Dosage Forms

  • Double strength tablet
  • Tablet
  • Suspension

Dosage & Administration

  • Dosage for mild to moderate infections
  • Dosage for severe infections
  • Long term therapy dosage
  • Gonorrhea treatment dosage

Contraindications

  • Hypersensitivity to trimethoprim or sulphonamides
  • Megaloblastic anaemia due to folate deficiency
  • Severe liver parenchymal damage
  • Blood dyscrasia
  • Severe renal insufficiency
  • Glucose 6-phosphate dehydrogenase deficiency

Side Effects

  • Crystalluria
  • Allergic reactions
  • Haemolysis
  • Thrombocytopenia
  • Neutropenia
  • Agranulocytosis
  • Malaise
  • Headache
  • Nausea
  • Vomiting

Pregnancy & Lactation

  • Excretion in breast milk
  • Risks of kernicterus

Precautions & Warnings

  • Risk of macrocytic anaemia
  • Interference in the conversion of Folic acid into Folinic acid
  • Reversal with Folinic acid
  • Interaction with sulphonylurea drug

Therapeutic Class

  • Anti-diarrhoeal
  • Sulphonamides
  • Trimethoprim

Storage Conditions

  • Temperature below 30°C
  • Protection from light
  • Protection from moisture
  • Keep out of reach of children

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