Seftrim (200 mg+40 mg)/5 ml (Oral Suspension)

60 ml bottle: ৳ 17.00

Medicine Details

Category	Details
Generic	Sulphamethoxazole trimethoprim
Company	Hudson pharmaceuticals ltd
Also available as	Seftrim ds 800 mg tablet Hi floxin 400 mg tablet Hi floxin 200 mg suspension

Title

Cotrimoxazole

Categories

Medicine
Antibiotics
Anti-infective

Description

Broad spectrum bactericidal activity against a wide range of gram-positive & gram-negative bacteria and some protozoa.

Indications

Respiratory tract infections
Genito-urinary tract infections
Gastro-intestinal tract infections
Osteomyelitis
Brucellosis
Skin infections
Septicaemia
Bacillary dysentery
Cholera

Pharmacology

Broad spectrum bactericidal activity
Blockade of bacterial enzyme systems in the biosynthesis of folinic acid

Dosage and administration

Recommended dosage for adults and children over 12 years
Different dosage for mild to severe infections
Long term therapy guidelines
Specific dosage for gonorrhoea
Dosage for children under 12 years

Contraindications

Hypersensitivity to trimethoprim or sulphonamides
Megaloblastic anaemia due to folate deficiency
Liver parenchymal damage
Blood dyscrasia
Severe renal insufficiency
Glucose 6-phosphate dehydrogenase deficiency

Side effects

Crystalluria
Allergic reactions
Haemolysis
Thrombocytopenia
Neutropenia
Agranulocytosis
Malaise
Headache
Nausea
Vomiting

Pregnancy and lactation

Avoid during pregnancy and nursing period
Sulphonamides excreted in breast milk
Potential risk of kernicterus

Precautions and warnings

Risk of macrocytic anaemia with prolonged treatment
Interference with Folic acid conversion
Reversible with Folinic acid administration
Caution with diabetic patients receiving sulphonylurea drugs

Therapeutic class

Anti-diarrhoeal Antimicrobial drugs
Sulphonamides & Trimethoprim

Storage conditions

Store below 30°C
Away from light & moisture
Keep out of the reach of children

Related Brands