Semotrim (200 mg+40 mg)/5 ml (Oral Suspension)

60 ml bottle: ৳ 22.00

Medicine Details

Category Details
Generic Sulphamethoxazole trimethoprim
Company Reliance pharmaceuticals ltd
Also available as
Semotrim 400 mg tablet

Title

Cotrimoxazole Double Strength Tablet

Categories

  • Medicine
  • Antibiotic
  • Antimicrobial

Description

Cotrimoxazole is bactericidal in vitro to a wide range of Gram-positive and Gram-negative organisms. It is used to treat respiratory tract, genito-urinary tract, and gastrointestinal tract infections, as well as other infections caused by susceptible organisms.

Dimensions

  • TabletSize: Double strength tablet
  • AgeRange: Over 12 years
  • SuspensionAgeRange: Under 12 years

ColorOptions

  • White

Functions

  • Bactericidal activity
  • Treatment of chronic bronchitis
  • Treatment of urinary tract infections

Materials

  • Trimethoprim
  • Sulphamethoxazole

TechnicalSpecifications

  • CombinationRatio: 1:5 (Trimethoprim:Sulphamethoxazole)

DesignElements

  • PharmacologicalAction: Broad spectrum bactericidal activity
  • MechanismOfAction: Blockade of bacterial enzyme systems

UsabilityFeatures

  • DosageForm:
    • Tablet
    • Suspension
  • DosageInstructions:
    • Mild to moderate infections: 1-2 tablets twice daily
    • Severe infections: 1.5-2 tablets twice daily
    • Long term therapy (>14 days): 0.5-1 tablet twice daily
    • Gonorrhea: 2-2.5 tablets every 12 hours
  • Contraindications:
    • Hypersensitivity to trimethoprim or sulphonamides
    • Megaloblastic anemia due to folate deficiency
    • Liver parenchymal damage
    • Severe renal insufficiency
    • Glucose 6-phosphate dehydrogenase deficiency
  • SideEffects:
    • Crystalluria
    • Allergic reactions
    • Haemolysis
    • Thrombocytopenia
    • Neutropenia
    • Agranulocytosis
    • Malaise
    • Headache
    • Nausea
    • Vomiting
  • PregnancyAndLactation: Excretion in breast milk, potential to cause kernicterus
  • Precautions:
    • Risk of macrocytic anaemia
    • Interference with conversion of Folic acid into Folinic acid
    • Potential potentiation of action of sulfonylurea in diabetic patients
  • TherapeuticClass: Anti-diarrhoeal Antimicrobial drugs, Sulphonamides & Trimethoprim
  • StorageConditions: Below 30°C temperature, away from light & moisture, keep out of reach of children

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