Sinatrim (200 mg+40 mg)/5 ml (Oral Suspension)

60 ml bottle: ৳ 22.00

Medicine Details

Category	Details
Generic	Sulphamethoxazole trimethoprim
Company	Ibn sina pharmaceuticals ltd
Also available as	Sinatrim 800 mg tablet

Indications

Respiratory tract infections
Acute and chronic bronchitis
Bronchiectasis
Lung abscess
Pneumocystis carinii pneumonitis
Sinusitis
Otitis media
Genito-urinary tract infections
Urethritis
Acute and chronic cystitis
Pyelonephritis
Prostatitis
Gonorrhoea
Gastro-intestinal tract infections
Salmonella infections
Chronic carrier state
Osteomyelitis
Brucellosis
Skin infections
Septicaemia
Dysentery
Cholera
Nocardiosis
Mycetoma

Pharmacology

Bactericidal activity
Broad spectrum against gram-positive bacteria
Broad spectrum against gram-negative bacteria
Protozoal activity
Blockade of bacterial enzyme systems
Biosynthesis of folinic acid inhibition

Dosage & Administration

Double strength tablet for over 12 years
Tablet for over 12 years
Tablet suspension for under 12 years
Mild to moderate infection dosage
Severe infection dosage
Long term therapy dosage
Gonorrhoea treatment dosage

Contraindications

Hypersensitivity to trimethoprim or sulphonamides
Megaloblastic anaemia due to folate deficiency
Liver parenchymal damage
Blood dyscrasia
Severe renal insufficiency
Glucose 6-phosphate dehydrogenase deficiency

Side Effects

Crystalluria
Allergic reactions
Haemolysis
Thrombocytopenia
Neutropenia
Agranulocytosis
Malaise
Headache
Nausea
Vomiting

Pregnancy & Lactation

Excretion in breast milk
Kernicterus risk

Precautions & Warnings

Risk of macrocytic anaemia
Interference in Folic acid conversion
Reversibility with Folinic acid
Caution with diabetic patients
Interactions with sulphonylurea drug

Therapeutic Class

Antidiarrheal antimicrobial drugs
Sulphonamides
Trimethoprim

Storage Conditions

Temperature below 30°C
Protection from light
Protection from moisture
Keep out of reach of children

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