Sitrim (200 mg+40 mg)/5 ml (Oral Suspension)

60 ml bottle: ৳ 20.07

Medicine Details

Category Details
Generic Sulphamethoxazole trimethoprim
Company Silva pharmaceuticals ltd
Also available as
Sitrim 400 mg tablet

Indications

  • Respiratory tract infections
  • Bronchitis
  • Pneumonia
  • Sinusitis
  • Otitis media
  • Genito-urinary tract infections
  • Cystitis
  • Pyelonephritis
  • Prostatitis
  • Gonorrhoea
  • Gastro-intestinal tract infections
  • Osteomyelitis
  • Brucellosis
  • Skin infections
  • Septicaemia
  • Bacillary dysentery
  • Cholera
  • Nocardiosis
  • Mycetoma

Pharmacology

  • Broad-spectrum bactericidal activity
  • Gram-positive bacteria
  • Gram-negative bacteria
  • Protozoa
  • Biosynthesis of folinic acid
  • Enzyme systems

Dosage & Administration

  • Dosage for different age groups
  • Dosage for mild to severe infections
  • Long-term therapy dosage
  • Administration frequency

Contraindications

  • Hypersensitivity to trimethoprim or sulphonamides
  • Megaloblastic anaemia
  • Liver parenchymal damage
  • Blood dyscrasia
  • Severe renal insufficiency
  • Glucose 6-phosphate dehydrogenase deficiency

Side Effects

  • Crystalluria
  • Allergic reactions
  • Haemolysis
  • Thrombocytopenia
  • Neutropenia
  • Agranulocytosis
  • Malaise
  • Headache
  • Nausea
  • Vomiting

Pregnancy & Lactation

  • Excretion in breast milk
  • Risk of kernicterus

Precautions & Warnings

  • Risk of macrocytic anaemia
  • Interference with Folic acid conversion
  • Reversal with Folinic acid
  • Interaction with sulphonylurea drug

Therapeutic Class

  • Anti-diarrhoeal antimicrobial drugs
  • Sulphonamides
  • Trimethoprim

Storage Conditions

  • Temperature below 30°C
  • Protection from light & moisture
  • Keep out of reach of children

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