Triprim DS 800 mg+160 mg (Tablet)

ProductTitle

• Cotrimoxazole Double Strength Tablet

Categories

• Medicine
• Antibiotic
• Antimicrobial
• Sulphonamide
• Trimethoprim
• Anti-Diarrhoeal

Description

• Bactericidal in vitro to a wide range of Gram-positive and Gram-negative organisms
• Broad spectrum bactericidal activity against a wide range of bacteria and some protozoa
• Exerts its bactericidal action by the sequential blockade of two bacterial enzyme systems in the biosynthesis of folinic acid in the microorganisms
• Dosage & Administration instructions for different age groups and infection severities
• Contraindications including hypersensitivity to trimethoprim or sulphonamides
• Rare side effects including crystalluria, allergic reactions, haemolysis, thrombocytopenia, neutropenia, agranulocytosis
• Precautions & Warnings regarding prolonged full dose treatment and diabetic patients
• Therapeutic Class as Anti-Diarrhoeal Antimicrobial drugs, Sulphonamides & Trimethoprim
• Storage Conditions to keep below 30°C temperature, away from light & moisture

Indications

• Bactericidal activity against a wide range of organisms including Streptococcus, Staphylococcus, Pneumococcus, Neisseria, E. coli, Haemophilus, Salmonella, Shigella, Vibrio cholerae, Brucella, Pneumocystis carinii, Nocardia, and Bordetella
• Suitable for respiratory, genito-urinary, gastro-intestinal, and other infections
• Particularly suitable for the treatment of chronic bronchitis and urinary tract infections

Pharmacology

• Broad spectrum bactericidal activity against a wide range of gram-positive & gram-negative bacteria and some protozoa

DosageAndAdministration

• Different dosages for Cotrimoxazole double strength tablet and suspension for different age groups
• Dosage variation for mild to severe infections, long term therapy, and gonorrhea

Contraindications

• Hypersensitivity to trimethoprim or sulphonamides
• Megaloblastic anaemia due to folate deficiency
• Liver parenchymal damage, blood dyscrasia, severe renal insufficiency, glucose 6-phosphate dehydrogenase deficiency

SideEffects

• Rare side effects such as crystalluria, allergic reactions, haemolysis, thrombocytopenia, neutropenia, agranulocytosis
• Less serious side effects include malaise, headache, nausea, and vomiting

PregnancyAndLactation

• Excretion in breast milk may cause kernicterus

PrecautionsAndWarnings

• Risk of macrocytic anaemia with prolonged full dose treatment
• Possible potentiation of action of sulphonylurea in diabetic patients receiving sulphonylurea drug

StorageConditions

• Keep below 30°C temperature, away from light & moisture

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