Cotrimox (200 mg+40 mg)/5 ml (Oral Suspension)

60 ml bottle: ৳ 21.00

Medicine Details

Category Details
Generic Sulphamethoxazole trimethoprim
Company Indo bangla pharmaceutical
Also available as
Cotrimox 400 mg tablet Cotrimox ds 800 mg tablet

Title

  • Cotrimoxazole Double Strength Tablet
  • Cotrimoxazole Tablet
  • Cotrimoxazole Suspension

Categories

  • Antibacterial
  • Antimicrobial
  • Anti-diarrhoeal
  • Sulphonamide
  • Trimethoprim

Description

  • Bactericidal against a wide range of bacteria and some protozoa
  • Exerts bactericidal action by sequential blockade of bacterial enzyme systems
  • Dosage and administration instructions for different age groups
  • Contraindications and hypersensitivity warnings
  • Rare reported side effects like crystalluria, haemolysis, and thrombocytopenia
  • Pregnancy and lactation precautions
  • Storage conditions below 30°C away from light and moisture
  • Therapeutic class as antimicrobial and sulphonamide agent

Color Options

  • White
  • Varies by brand

Functions

  • Treatment of respiratory tract infections
  • Management of genito-urinary tract infections
  • Combatting gastro-intestinal tract infections
  • Addressing other infections confirmed to be susceptible to Cotrimoxazole
  • Adjuvant use in cholera with fluid and electrolyte replacement

Materials

  • Trimethoprim
  • Sulphamethoxazole
  • Folinic acid

Technical Specifications

  • Double strength tablet suitable for individuals over 12 years
  • Tablet for individuals over 12 years
  • Suspension for children under 12 years

Design Elements

  • Tablet form
  • Suspension form

Usability Features

  • Mild to severe infection management
  • Long-term therapy option for over 14 days

Dimensions

  • Varies by dosage form

Indications

  • Bactericidal to a wide range of Gram-positive and Gram-negative organisms
  • Particularly high activity against specific bacteria such as Haemophilus influenzae, E. coli, and Proteus spp.
  • Treatment of chronic bronchitis, urinary tract infections, osteomyelitis, brucellosis, skin infections, septicaemia, and other confirmed susceptible infections

Pharmacology

  • Broad-spectrum bactericidal activity against gram-positive and gram-negative bacteria
  • Sequential blockade of bacterial enzyme systems in the biosynthesis of folinic acid

Dosage & Administration

  • Specific dosages for mild to severe infections based on age and formulation
  • Different dosages for long-term therapy and gonorrhea

Contraindications

  • Hypersensitivity to trimethoprim or sulphonamides
  • Megaloblastic anaemia due to folate deficiency
  • Liver parenchymal damage, blood dyscrasia, severe renal insufficiency, glucose 6-phosphate dehydrogenase deficiency

Side Effects

  • Reported rare side effects include crystalluria, allergic reactions, haemolysis, thrombocytopenia, and agranulocytosis
  • Transient and less serious side effects such as malaise, headache, nausea, and vomiting

Pregnancy & Lactation

  • Avoid during pregnancy and nursing period due to potential risks of placental transfer and excretion in breast milk

Precautions & Warnings

  • Prolonged full-dose treatment associated with the risk of macrocytic anaemia
  • Potential interaction with sulphonylurea drugs in diabetic patients

Therapeutic Class

  • Anti-diarrhoeal Antimicrobial drugs
  • Sulphonamides & Trimethoprim

Storage Conditions

  • Keep below 30°C temperature
  • Protect from light and moisture
  • Keep out of the reach of children

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