Cotrimox DS 800 mg+160 mg (Tablet)

Unit Price: ৳ 2.00 (100's pack: ৳ 200.00)

Medicine Details

Title

  • Cotrimoxazole Tablet

Categories

  • Antibiotics
  • Antimicrobial Drugs
  • Sulphonamides
  • Trimethoprim

Indications

  • Treatment of respiratory tract infections
  • Treatment of genito-urinary tract infections
  • Treatment of gastrointestinal tract infections
  • Treatment of osteomyelitis
  • Treatment of skin infections
  • Treatment of septicaemia

Pharmacology

  • Broad-spectrum bactericidal activity
  • Sequential blockade of bacterial enzyme systems
  • Biosynthesis of folinic acid

Dosage and Administration

  • Double strength tablet for patients over 12 years
  • Tablet for patients over 12 years
  • Suspension for patients under 12 years

Contraindications

  • Hypersensitivity to trimethoprim or sulphonamides
  • Megaloblastic anaemia due to folate deficiency
  • Liver parenchymal damage
  • Blood dyscrasia
  • Severe renal insufficiency
  • Glucose 6-phosphate dehydrogenase deficiency

Side Effects

  • Crystalluria
  • Allergic reactions
  • Haemolysis
  • Thrombocytopenia
  • Neutropenia
  • Agranulocytosis
  • Malaise
  • Headache
  • Nausea
  • Vomiting

Pregnancy and Lactation

  • Excretion in breast milk
  • Risk of kernicterus

Precautions and Warnings

  • Risk of macrocytic anaemia
  • Interference with Folic acid conversion
  • Reversal with Folinic acid
  • Potentiation of sulphonylurea drug action in diabetic patients

Therapeutic Class

  • Anti-diarrhoeal Antimicrobial drugs
  • Sulphonamides & Trimethoprim

Storage Conditions

  • Keep below 30°C
  • Away from light and moisture
  • Keep out of reach of children

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