Doctrim 400 mg+80 mg (Tablet)

Indications

• Respiratory tract infections
• Genito-urinary tract infections
• Gastro-intestinal tract infections
• Osteomyelitis
• Brucellosis
• Skin infections
• Septicaemia
• Dysentery
• Cholera
• Nocardiosis
• Mycetoma

Pharmacology

Broad spectrum bactericidal activity

Dosage & Administration

• Dosage for mild to moderate infections
• Dosage for severe infections
• Long term therapy dosage
• Gonorrhoea dosage

Contraindications

• Hypersensitivity to trimethoprim or sulphonamides
• Megaloblastic anaemia due to folate deficiency
• Liver parenchymal damage
• Blood dyscrasia
• Severe renal insufficiency
• Glucose 6-phosphate dehydrogenase deficiency

Side Effects

• Crystalluria
• Allergic reactions
• Haemolysis
• Thrombocytopenia
• Neutropenia
• Agranulocytosis
• Malaise
• Headache
• Nausea
• Vomiting

Pregnancy & Lactation

Passage of sulphonamides

Precautions & Warnings

• Risk of macrocytic anaemia
• Interference in the conversion of Folic acid into Folinic acid
• Advice for diabetic patients

Therapeutic Class

Anti-diarrhoeal Antimicrobial drugs

Storage Conditions

Avoid light & moisture, Keep out of the reach of children