Fimoxyclav (125 mg+31.25 mg)/5 ml (Powder for Suspension)

100 ml bottle: ৳ 245.74

Medicine Details

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Genito-urinary tract infections
  • Skin and soft tissue infections
  • Bone and joint infections
  • Intra-abdominal sepsis

Composition

  • 375 mg tablet
  • 625 mg tablet
  • 1 gm tablet
  • Powder for Suspension
  • Powder for Suspension (Forte)
  • 1.2 gm Injection
  • 0.6 gm injection

Pharmacology

  • Broad spectrum of bactericidal activity
  • Antibiotic combination of Amoxicillin and Clavulanic Acid
  • Inactivation of beta-lactamase enzymes

Dosage

  • For adults and children over 12 years
  • Different dosage for different types of infections
  • Recommended dosage for IV Injection

Administration

  • Oral dosage form
  • IV injection administration

Interaction

  • Prolongation of bleeding time
  • Reduction of efficacy of oral contraceptives
  • Concomitant use of allopurinol

Contraindications

  • History of Penicillin hypersensitivity
  • Possible cross-sensitivity with other beta-lactam antibiotics

Side Effects

  • Diarrhoea
  • Indigestion
  • Nausea
  • Hepatitis
  • Urticarial rashes
  • Angioedema
  • Anaphylaxis

Pregnancy & Lactation

  • No teratogenic effect in animal studies
  • Limited use during human pregnancy
  • Detection of Amoxicillin in breast milk

Precautions & Warnings

  • Use with care in patients on anticoagulation therapy
  • Dosage adjustment for renal impairment
  • Maintenance of adequate fluid intake

Use in Special Populations

  • Dose adjustment for renal impairment in adults and children
  • Monitoring of hepatic function

Overdose Effects

  • Unlikely occurrence of overdose problems
  • Possible gastrointestinal symptoms

Therapeutic Class

  • Broad spectrum penicillins

Reconstitution

  • Reconstitution of IV injection
  • Guidelines for IV injection reconstitution

Storage Conditions

  • Storage below 25°C
  • Protection from light and moisture
  • Refrigeration of reconstituted suspension
  • 20-minute usage window for reconstituted vial

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