Sytrim DS 800 mg+160 mg (Tablet)

Unit Price: ৳ 2.00 (50's pack: ৳ 100.00)

Medicine Details

Indications

  • Respiratory tract infections
  • Genito-urinary tract infections
  • Gastro-intestinal tract infections
  • Osteomyelitis
  • Brucellosis
  • Septicaemia
  • Bacillary dysentery
  • Skin infections

Pharmacology

Cotrimoxazole has broad-spectrum bactericidal activity against a wide range of gram-positive and gram-negative bacteria.

Dosage & Administration

  • Cotrimoxazole double strength tablet:
    • Mild to moderate infections: 1 tablet twice daily
    • Severe infections: 1.5 tablets twice daily
    • Long term therapy (>14 days): 0.5 tablet twice daily
    • Gonorrhoea: 2 tablets every 12 hours for two days or 2.5 tablets followed by a further dose of 2.5 tablets after 8 hours
  • Cotrimoxazole tablet:
    • Mild to moderate infections: 2 tablets twice daily
    • Severe infections: 2 tablets thrice daily
    • Long term therapy (>14 days): 1 tablet twice daily
  • Cotrimoxazole suspension:
    • 6-12 years: 2 teaspoonful twice daily
    • 6 month-5 years: 1 teaspoonful twice daily
    • 6 weeks-6 months: 0.5 teaspoonful twice daily

Contraindications

  • Hypersensitivity to trimethoprim or sulphonamides
  • Megaloblastic anaemia due to folate deficiency
  • Liver parenchymal damage
  • Blood dyscrasia
  • Severe renal insufficiency
  • Glucose 6-phosphate dehydrogenase deficiency

Side Effects

  • Crystalluria
  • Allergic reactions
  • Haemolysis
  • Thrombocytopenia
  • Neutropenia
  • Agranulocytosis
  • Malaise
  • Headache
  • Nausea
  • Vomiting

Pregnancy & Lactation

Sulphonamides pass through placenta and are excreted in breast milk, may cause kernicterus

Precautions & Warnings

Prolonged full-dose treatment is associated with the risk of macrocytic anaemia, care should be taken when giving to diabetic patients receiving sulphonylurea drug.

Therapeutic Class

Anti-diarrhoeal Antimicrobial drugs, Sulphonamides & Trimethoprim

Storage Conditions

Keep below 30°C temperature, away from light & moisture, keep out of the reach of children

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