Aprocin 0.3% (Ophthalmic Ointment)

3 gm tube: ৳ 35.00

Medicine Details

Category Details
Generic Ciprofloxacin ophthalmic
Company Aristopharma ltd
Also available as

Indications

  • Treatment of corneal ulcers
  • Treatment of conjunctivitis
  • Treatment of blepharitis
  • Infections caused by susceptible strains of bacteria

Composition

  • Each ml contains Ciprofloxacin Hydrochloride BP equivalent to Ciprofloxacin 3 mg
  • Preservative: Benzalkonium Chloride 0.06 mg

Pharmacology

  • In vitro activity against a wide range of Gram-negative organisms
  • Bactericidal action
  • Inhibition of DNA gyrase
  • Essential in bacterial DNA reproduction

Dosage & Administration

  • Specific dosage for corneal ulcers
  • Specific dosage for bacterial conjunctivitis
  • Specific dosage for blepharitis
  • Pediatric use safety

Interaction

  • Potential effects on theophylline plasma concentrations
  • Interference with caffeine metabolism
  • Enhanced effects of oral anticoagulant warfarin
  • Transient elevations in serum creatinine

Contraindications

  • Hypersensitivity to Ciprofloxacin
  • Hypersensitivity to other quinolones

Side Effects

  • Local burning or discomfort
  • White crystalline precipitates in corneal ulcer studies
  • Lid margin crusting
  • Foreign body sensation
  • Itching
  • Conjunctival hyperemia
  • Bad taste following instillation
  • Corneal staining
  • Allergic reactions
  • Nausea
  • Decreased vision

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Use during pregnancy justified if benefit outweighs risk

Precautions & Warnings

  • Prolonged use may result in overgrowth of non-susceptible organisms
  • Discontinue if super-infection occurs
  • Discontinue at first appearance of skin rash or hypersensitivity reaction

Overdose Effects

  • Topical overdose flushed with warm tap water

Therapeutic Class

  • Aural Anti-bacterial preparations
  • Ophthalmic antibacterial drugs

Storage Conditions

  • Store at room temperature
  • Protect from light
  • Do not use more than one month after opening

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