Ciprin 0.3% (Ophthalmic Ointment)

3 gm tube: ৳ 35.00

Medicine Details

Category Details
Generic Ciprofloxacin ophthalmic
Company Nipa pharmaceuticals ltd
Also available as
Ciprin 03 eye drop

Indications

  • Treatment of corneal ulcers
  • Treatment of conjunctivitis
  • Treatment of blepharitis

Composition

  • Active Substance: Ciprofloxacin Hydrochloride BP equivalent to Ciprofloxacin 3 mg per ml
  • Preservative: Benzalkonium Chloride 0.06 mg per ml

Pharmacology

  • Bactericidal activity against a wide range of Gram-negative and Gram-positive organisms
  • Inhibition of A subunits of DNA gyrase

Dosage & Administration

  • Dosage for corneal ulcers based on time intervals and frequency of instillation
  • Dosage for bacterial conjunctivitis and blepharitis based on hourly and daily instillation
  • Safety and effectiveness not established in children under 1 year of age

Interaction

  • Potential elevation of plasma concentrations of theophylline
  • Interference with the metabolism of caffeine
  • Enhancement of effects of oral anticoagulant warfarin and its derivatives
  • Transient elevations in serum creatinine in patients receiving cyclosporin concomitantly

Contraindications

  • Hypersensitivity to Ciprofloxacin or any other component of the product
  • Hypersensitivity to other quinolones, including Nalidixic acid

Side Effects

  • Local burning or discomfort
  • White crystalline precipitates in approximately 17% of patients in corneal ulcer studies
  • Lid margin crusting
  • Foreign body sensation
  • Itching
  • Conjunctival hyperemia
  • A bad taste following instillation
  • Corneal staining
  • Keratopathy/keratitis
  • Allergic reactions
  • Lid edema
  • Tearing
  • Photophobia
  • Corneal infiltrates
  • Nausea
  • Decreased vision

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Use during pregnancy only if potential benefit justifies potential risk to the fetus

Precautions & Warnings

  • Prolonged use may result in overgrowth of non-susceptible organisms, including fungi
  • Discontinue use and initiate alternative therapy if super-infection occurs
  • Discontinue at the first appearance of a skin rash or any other sign of hypersensitivity reaction

Overdose Effects

  • Flushing from the eye(s) with warm tap water in case of topical overdose

Therapeutic Class

  • Aural Anti-bacterial preparations
  • Ophthalmic antibacterial drugs

Storage Conditions

  • Store at room temperature
  • Protect from light
  • Contents should not be used more than one month after first opening of the bottle

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