Lox 0.3% (Ophthalmic Solution)

5 ml drop: ৳ 45.00

Medicine Details

Category Details
Generic Ciprofloxacin ophthalmic
Company Apex pharmaceuticals ltd

Indications

  • Treatment of corneal ulcers
  • Treatment of conjunctivitis
  • Treatment of blepharitis
  • Bacterial susceptibility

Composition

  • Active substance: Ciprofloxacin Hydrochloride BP equivalent to Ciprofloxacin 3 mg per ml eye drops
  • Preservative: Benzalkonium Chloride 0.06 mg per ml eye drops

Pharmacology

  • Inhibits DNA gyrase (topoisomerase)
  • Bactericidal activity
  • Wide range of Gram-negative and Gram-positive organism activity

Dosage & Administration

  • Corneal ulcers dosing regimen
  • Bacterial conjunctivitis/blepharitis dosing regimen
  • Pediatric use safety

Interactions

  • Elevation of plasma theophylline concentrations
  • Interference with caffeine metabolism
  • Enhancement of oral anticoagulant warfarin effects
  • Transient elevations in serum creatinine with cyclosporin

Contraindications

  • Hypersensitivity to Ciprofloxacin
  • Hypersensitivity to quinolones

Side Effects

  • Local burning or discomfort
  • Crystalline precipitates in corneal ulcer patients
  • Lid margin crusting
  • Foreign body sensation
  • Itching
  • Conjunctival hyperemia
  • Bad taste following instillation
  • Corneal staining
  • Keratopathy/keratitis
  • Allergic reactions
  • Lid edema
  • Tearing
  • Photophobia
  • Corneal infiltrates
  • Nausea
  • Decreased vision

Pregnancy & Lactation

  • Use during pregnancy if benefit justifies risk

Precautions & Warnings

  • Prolonged use may result in overgrowth of non-susceptible organisms
  • Super-infection precautions
  • Discontinue at hypersensitivity reaction appearance

Overdose Effects

  • Topical overdose flushing with warm tap water

Therapeutic Class

  • Aural anti-bacterial preparations
  • Ophthalmic antibacterial drugs

Storage Conditions

  • Store at room temperature
  • Protect from light
  • Use within one month after opening

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