Amiflox DS 250 mg/5 ml (Powder for Suspension)
60 ml bottle: ৳ 85.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ciprofloxacin |
| Company | Amico laboratories ltd |
| Also available as |
Indications
- Treatment of single infection or mixed infections
- Infections caused by susceptible organisms
- Infections resistant to other antibiotics
- Antibacterial activity
- Infections in urinary, respiratory, and gastrointestinal tracts
- Gonorrhoea and septicaemia treatment
- Severe systemic, respiratory, urinary, skin, soft tissue, gastrointestinal, biliary tract, intra abdominal, bone and joint, pelvic, eye, ear, nose and throat infections
- Gonorrhoea treatment in urethral, rectal, and pharyngeal areas
Pharmacology
- Synthetic quinolone anti-infective agent
- Broad spectrum of activity
- Active against gram-negative and gram-positive aerobic bacteria
- Bactericidal action by interference with DNA gyrase
- Rapid and well absorption from G.I. tract
- Widely distributed into body tissues and fluids
- Excretion in the urine
Dosage
- Determined by severity and type of infection
- Specific dosage range for adults, lower and upper urinary tract infections, respiratory tract infections, and gonorrhoea
- Dosage adjustment in impaired renal function
- No dosage adjustment in elderly
- Different dosage for adolescents and children
- Duration of treatment based on severity of infection
Administration
- Instructions for Ciprofloxacin IV infusion
- Checking the bag for leaks
- Proper fluid level in chamber during infusion
- Rate regulation of administration
Interaction
- Concurrent administration with specific products to be avoided
- Significantly reduced absorption with milk or dairy products
Contraindications
- History of hypersensitivity to Ciprofloxacin or other quinolones
Side Effects
- Gastrointestinal disturbances
- Central nervous system disturbances
- Hypersensitivity reactions
- Joint pain
- Photosensitivity
- Transient increase in liver enzymes
- Risk of hypoglycemia and mental health adverse effects
Pregnancy & Lactation
- No evidence of teratogenicity, impairment of fertility or peri/post-natal development in reproduction studies
- Potential risk of arthropathy
- Use not recommended during pregnancy
- Ciprofloxacin secretion in milk
Precautions & Warnings
- Caution in patients with suspected or known CNS disorders
- Fluid intake recommendation
- Concurrent administration to be avoided with specific products
- Significantly reduced absorption with milk or yogurt alone
Use in Special Populations
- Effective in clinical trials but not a drug of first choice in pediatric population
Overdose Effects
- Seizures, hallucinations, confusion
- Abdominal discomfort
- Renal and hepatic impairment
- Crystalluria and haematuria
- Reversible renal toxicity
Therapeutic Class
- 4-Quinolone preparations
- Anti-diarrhoeal antimicrobial drugs
Storage Conditions
- Keep below 30°C temperature
- Protected from light and moisture
- Keep out of the reach of children