Aprocin 500 mg (Tablet)

Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)
Strip Price: ৳ 150.00

Medicine Details

Category Details
Generic Ciprofloxacin
Company Aristopharma ltd
Also available as

Brand

  • Aprocin

Category

  • Medicine
  • Pharmaceutical

Indications

  • Treatment of single infection or mixed infections caused by susceptible organisms
  • Infections resistant to other antibiotics like Aminoglycosides, Penicillins, and Cephalosporins
  • Infections of urinary, respiratory, and gastrointestinal tracts
  • Septicaemia
  • Bacteraemia
  • Peritonitis
  • Immunosuppressed patients with haematological or solid tumors
  • Intensive care unit patients with specific problems like infected burns
  • Gonorrhoea
  • Respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Gastro-intestinal infections
  • Infection of the biliary tract
  • Intra abdominal infections
  • Bone and joint infections
  • Pelvic infections
  • Eye, ear, nose, and throat infections

Pharmacology

  • Synthetic quinolone anti-infective agent
  • Broad spectrum of activity
  • Active against gram negative aerobic bacteria including Enterobacteriaceae and Pseudomonas aeruginosa
  • Active against gram-positive aerobic bacteria including penicillinase producing, non penicillinase producing, and methicillin-resistant staphylococci
  • Bactericidal action results from interference with the enzyme DNA gyrase

Dosage

  • Dosage based on severity and type of infection, sensitivity of causative organism(s) and age, weight, and renal function
  • Adult dosage range: 100-750 mg twice daily
  • Lower and upper urinary tract infections dosage: 250-500 mg twice daily
  • Respiratory tract infections dosage: 250-500 mg twice daily
  • Gonorrhea dosage: Single dose of 250 or 500 mg
  • Majority of other infections dosage: 500-750 mg twice daily
  • Duration of treatment based on severity of infection and clinical response

Administration

  • Instruction for IV infusion of Ciprofloxacin
  • Checking bag for leaks
  • Not using if solution is cloudy or precipitate is present
  • Regulating rate of administration with flow control clamp

Interaction

  • Avoid concurrent administration with Magnesium or Aluminum containing antacids, sucralfate, or products containing Calcium, Iron, or Zinc
  • Avoid concurrent intake with milk or other dairy products

Contraindications

  • Hypersensitivity to Ciprofloxacin or other quinolones

Side effects

  • Gastrointestinal disturbances
  • Disturbances of the central nervous system
  • Hypersensitivity reactions
  • Joint pain
  • Mild photosensitivity
  • Transient increase in liver enzymes
  • Risk of hypoglycemia
  • Mental health adverse effects

Pregnancy and lactation

  • Not recommended during pregnancy due to arthropathy in immature animals
  • Not recommended for nursing mothers due to secretion in milk

Precautions and warnings

  • Use with caution in patients with suspected or known CNS disorders
  • Drink fluids liberally while taking
  • Avoid concurrent administration with magnesium/aluminium antacids, sucralfate, or products containing calcium, iron, and zinc
  • Avoid concurrent intake with milk or yogurt alone

Use in special populations

  • Not a drug of first choice in pediatric population

Overdose effects

  • Seizures
  • Hallucinations
  • Confusion
  • Abdominal discomfort
  • Renal and hepatic impairment
  • Crystalluria
  • Reversible renal toxicity

Therapeutic class

  • 4-Quinolone preparations
  • Anti-diarrhoeal Antimicrobial drugs

Storage conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

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