Beuflox 250 mg/sachet (Oral Powder)

250 mg sachet: ৳ 12.00 (14's pack: ৳ 168.00)

Medicine Details

Indications

  • Treatment of single infection or mixed infections caused by susceptible organisms
  • Infections resistant to other antibiotics
  • Infections of urinary, respiratory, and gastrointestinal tracts
  • Gonorrhoea and septicaemia treatment
  • Infections of skin, soft tissue, and biliary tract
  • Intra abdominal, bone, joint, and pelvic infections
  • Eye, ear, nose, and throat infections
  • Severe systemic infections
  • Gastro-intestinal and pelvic infections
  • Treatment of various infections caused by sensitive bacteria
  • Treatment of infected burns and wounds

Pharmacology

  • Synthetic quinolone anti-infective agent
  • Broad spectrum of activity
  • Active against gram-negative aerobic bacteria
  • Active against gram-positive aerobic bacteria
  • Bactericidal action, interference with DNA gyrase
  • Rapid and well absorption from G.I. tract
  • Widely distributed in body tissues and fluids
  • Excretion in urine
  • Half-life of about 3.5 hours

Dosage

  • Dosage determined by severity, type of infection, and patient's factors
  • Dosage range for adults: 100-750 mg twice daily
  • Various dosage recommendations based on infection type
  • Dosage adjustment in impaired renal function
  • Duration of treatment based on severity and clinical response
  • Specific dosages for cystic fibrosis
  • Dosage recommendations for adolescents and children

Administration

  • Instructions for the use of IV infusion
  • Specific instructions for checking the IV solution
  • Guidelines for regulating rate of administration

Interaction

  • Avoid concurrent administration with certain antacids and products
  • Avoid concurrent use with milk or dairy products

Contraindications

  • History of hypersensitivity to Ciprofloxacin or quinolones

Side Effects

  • Gastrointestinal disturbances
  • Central nervous system disturbances
  • Hypersensitivity reactions
  • Joint pain, photosensitivity
  • Transient increase in liver enzymes and other serum levels

Pregnancy & Lactation

  • Reproduction studies in mice, rats, and rabbits
  • No evidence of teratogenicity, impairment of fertility or peri/post natal development
  • Caution due to arthropathy in immature animals
  • Not recommended during pregnancy or nursing

Precautions & Warnings

  • Caution in patients with CNS disorders
  • Instructions on administration with or without meals
  • Guidelines on concurrent administration with antacids and dairy products

Use in Special Populations

  • Effective in clinical trials but not a drug of first choice in pediatric population

Overdose Effects

  • Seizures, hallucinations, confusion
  • Abdominal discomfort, renal and hepatic impairment
  • Crystalluria, haematuria, reversible renal toxicity

Therapeutic Class

  • 4-Quinolone preparations
  • Anti-diarrhoeal antimicrobial drugs

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light and moisture
  • Keep out of the reach of children

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