Beuflox 250 mg/sachet (Oral Powder)
250 mg sachet: ৳ 12.00 (14's pack: ৳ 168.00)
Medicine Details
Category | Details |
---|---|
Generic | Ciprofloxacin |
Company | Incepta pharmaceuticals ltd |
Also available as |
Indications
- Treatment of single infection or mixed infections caused by susceptible organisms
- Infections resistant to other antibiotics
- Infections of urinary, respiratory, and gastrointestinal tracts
- Gonorrhoea and septicaemia treatment
- Infections of skin, soft tissue, and biliary tract
- Intra abdominal, bone, joint, and pelvic infections
- Eye, ear, nose, and throat infections
- Severe systemic infections
- Gastro-intestinal and pelvic infections
- Treatment of various infections caused by sensitive bacteria
- Treatment of infected burns and wounds
Pharmacology
- Synthetic quinolone anti-infective agent
- Broad spectrum of activity
- Active against gram-negative aerobic bacteria
- Active against gram-positive aerobic bacteria
- Bactericidal action, interference with DNA gyrase
- Rapid and well absorption from G.I. tract
- Widely distributed in body tissues and fluids
- Excretion in urine
- Half-life of about 3.5 hours
Dosage
- Dosage determined by severity, type of infection, and patient's factors
- Dosage range for adults: 100-750 mg twice daily
- Various dosage recommendations based on infection type
- Dosage adjustment in impaired renal function
- Duration of treatment based on severity and clinical response
- Specific dosages for cystic fibrosis
- Dosage recommendations for adolescents and children
Administration
- Instructions for the use of IV infusion
- Specific instructions for checking the IV solution
- Guidelines for regulating rate of administration
Interaction
- Avoid concurrent administration with certain antacids and products
- Avoid concurrent use with milk or dairy products
Contraindications
- History of hypersensitivity to Ciprofloxacin or quinolones
Side Effects
- Gastrointestinal disturbances
- Central nervous system disturbances
- Hypersensitivity reactions
- Joint pain, photosensitivity
- Transient increase in liver enzymes and other serum levels
Pregnancy & Lactation
- Reproduction studies in mice, rats, and rabbits
- No evidence of teratogenicity, impairment of fertility or peri/post natal development
- Caution due to arthropathy in immature animals
- Not recommended during pregnancy or nursing
Precautions & Warnings
- Caution in patients with CNS disorders
- Instructions on administration with or without meals
- Guidelines on concurrent administration with antacids and dairy products
Use in Special Populations
- Effective in clinical trials but not a drug of first choice in pediatric population
Overdose Effects
- Seizures, hallucinations, confusion
- Abdominal discomfort, renal and hepatic impairment
- Crystalluria, haematuria, reversible renal toxicity
Therapeutic Class
- 4-Quinolone preparations
- Anti-diarrhoeal antimicrobial drugs
Storage Conditions
- Keep below 30°C temperature
- Protected from light and moisture
- Keep out of the reach of children