Moxaclav (125 mg+31.25 mg)/5 ml (Powder for Suspension)

100 ml bottle: ৳ 220.00

Medicine Details

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Genito-urinary tract infections
  • Skin and soft tissue infections
  • Bone and joint infections
  • Other infections

Composition

  • 375 mg tablet
  • 625 mg tablet
  • 1 gm tablet
  • Powder for Suspension
  • Powder for Suspension (Forte)
  • 1.2 gm Injection
  • 0.6 gm injection

Pharmacology

  • Antibacterial combination
  • Amoxicillin
  • Clavulanic Acid
  • Bactericidal activity
  • Broad spectrum
  • Beta-lactamase inhibitor
  • Microorganism susceptibility
  • Pharmacokinetics
  • Peak serum levels
  • Absorption
  • Serum binding

Dosage

  • Adult dosage
  • Children dosage
  • Tablet dosage
  • Suspension dosage
  • Forte suspension dosage
  • IV Injection dosage
  • Dosage adjustment
  • Surgical prophylaxis

Administration

  • Oral dosage form
  • IV injection administration
  • Intravenous injection
  • Slow intravenous infusion
  • Gastrointestinal intolerance
  • Injection discard

Interaction

  • Prolongation of bleeding time
  • Prothrombin time
  • Reduction of oral contraceptives efficacy
  • Concomitant use of allopurinol
  • Allergic skin reactions

Contraindications

  • Penicillin hypersensitivity
  • Cross-sensitivity with beta-lactam antibiotics
  • Cholestatic jaundice history

Side Effects

  • Mild and transitory side effects
  • Gastrointestinal side effects
  • Hepatitis
  • Cholestatic jaundice
  • Allergic skin reactions
  • Angioedema
  • Anaphylaxis

Pregnancy & Lactation

  • Animal teratogenic studies
  • Limited human pregnancy usage
  • Breast milk trace quantities

Precautions & Warnings

  • Anticoagulation therapy
  • Severe hepatic dysfunction
  • Renal impairment
  • High dose administration
  • Fluid intake maintenance
  • Crystalluria possibility
  • Hepatic function monitoring

Use in Special Populations

  • Renal impairment dosage adjustment
  • Hepatic impairment caution
  • Dialysis effect on serum concentrations

Overdose Effects

  • Unlikely occurrence
  • Gastrointestinal symptoms
  • Fluid and electrolyte balance disturbance
  • Haemodialysis removal

Therapeutic Class

  • Broad spectrum penicillins

Reconstitution

  • IV injection reconstitution
  • Reconstitution instructions
  • Incompatible mixtures

Storage Conditions

  • Temperature
  • Light and moisture protection
  • Refrigeration of reconstituted suspension
  • Reconstituted vial usage duration

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