Civox 200 mg/5 ml (Powder for Suspension)

60 ml bottle: ৳ 90.35

Medicine Details

Category Details
Generic Ciprofloxacin
Company Popular pharmaceuticals ltd
Also available as
Civox 500 mg tablet Civox 200 mg injection

Title

  • Civox

Categories

  • Medicine
  • Antibacterial
  • Anti-infective

Description

  • Ciprofloxacin is indicated for the treatment of various infections caused by susceptible organisms, with extensive tissue penetration and enhanced antibacterial activity.

DosageRangeAdults

100-750 mg twice daily

DosageUrinaryTractInfections

  • 250-500 mg twice daily
  • Uncomplicated and complicated urethritis, cystitis, pyelonephritis, prostatitis, epididymitis

DosageRespiratoryTractInfections

  • 250-500 mg twice daily
  • Lobar and bronchopneumonia, acute and chronic bronchitis, acute exacerbation of cystic fibrosis, bronchiectasis, empyema

DosageGonorrhea

Single dose of 250 or 500 mg

DosageCysticFibrosis

750 mg twice daily

DosageRenalFunction

Dosage adjustment may be required for patients with impaired renal function

DosageElderly

No dosage adjustment necessary for the elderly

DosageAdolescentsChildren

7.5-15 mg/kg/day depending upon the severity of infection, administered in two divided doses

DosageDurationOfTreatment

The duration of treatment depends upon the severity of infection, clinical response, and bacteriological findings

DosageExtendedReleaseTablet

1000 mg tablet once daily for three days in uncomplicated urinary tract infection

DosageIVInfusion

  • UrinaryTractInfection: Mild to Moderate: 200-400 mg 12 hourly for 7-14 days; Severe or Complicated: 400 mg 8-12 hourly for 7-14 days
  • LowerRespiratoryTractInfection: Mild to Moderate: 200-400 mg 12 hourly for 7-14 days; Severe or Complicated: 400 mg 8-12 hourly for 7-14 days
  • NosocomialPneumonia: 400 mg 8-12 hourly for 10-14 days
  • SkinAndSkinStructure: Mild to Moderate: 400 mg 12 hourly for 7-14 days; Severe or Complicated: 400 mg 8-12 hourly for 7-14 days
  • BoneAndJointInfection: Mild to Moderate: 400 mg 12 hourly for more than 4-6 weeks; Severe/Complicated: 400 mg 8-12 hourly for more than 4-6 weeks
  • IntraabdominalAcuteAbdomen: Complicated: 400 mg 12 hourly for 7-14 days
  • AcuteSinusitis: Mild/Moderate: 400 mg 12 hourly for 10 days
  • ChronicBacterialProstatitis: Mild/Moderate: 400 mg 12 hourly for 28 days

Indications

  • SevereSystemicInfections:
    • Septicaemia
    • Bacteraemia
    • Peritonitis
    • Immunosuppressed patients with haematological or solid tumors
    • Patients in intensive care unit with specific problems such as infected burns
  • RespiratoryTractInfections:
    • Lobar and bronchopneumonia
    • Acute and chronic bronchitis
    • Acute exacerbation of cystic fibrosis
    • Bronchiectasis
    • Empyema
  • UrinaryTractInfections:
    • Uncomplicated and complicated urethritis
    • Cystitis
    • Pyelonephritis
    • Prostatitis
    • Epididymitis
  • SkinAndSoftTissueInfections:
    • Infected ulcers
    • Wound infections
    • Abscesses
    • Cellulitis
    • Otitis externa
    • Erysipelas
    • Infected burns
  • GastroIntestinalInfections:
    • Enteric fever
    • Infective diarrhea
  • BiliaryTractInfection:
    • Cholangitis
    • Cholecystitis
    • Empyema of the gall bladder
  • IntraAbdominalInfections:
    • Peritonitis
    • Intra abdominal abscesses
  • BoneAndJointInfection:
    • Osteomyelitis
    • Septic arthritis
  • PelvicInfections:
    • Salpingitis
    • Endometritis
    • Pelvic inflammatory diseases
  • EyeEarNoseThroatInfections:
    • Otitis media
    • Sinusitis
    • Mastoiditis
    • Tonsillitis
  • Gonorrhea:
    • Urethral
    • Rectal
    • Pharyngeal gonorrhea caused by beta-lactamase producing organisms or organisms moderately sensitive to penicillin

Pharmacology

Ciprofloxacin is a synthetic quinolone anti-infective agent with broad spectrum of activity

ModeOfAction

The bactericidal action of Ciprofloxacin results from interference with the enzyme DNA gyrase needed for the synthesis of bacterial DNA

AdministrationInstructions

Instructions for the use of Ciprofloxacin IV infusion including checking for minute leaks, avoiding concurrent use with certain products, and regulating the rate of administration

InteractionPrecautions

Concurrent administration of Civox should be avoided with certain products and milk or yogurt alone, since absorption of Civox may be significantly reduced

Contraindications

Patients with a history of hypersensitivity to Ciprofloxacin or to other quinolones

SideEffects

  • Gastrointestinal disturbances
  • Disturbances of the central nervous system
  • Hypersensitivity reactions
  • Joint pain
  • Photosensitivity
  • Transient increase in liver enzymes
  • Risk of hypoglycemia & mental health adverse effects

PregnancyLactation

Use during pregnancy is not recommended due to the potential risk of arthropathy in immature animals, and administration to nursing mothers is not recommended

OverdoseEffects

Overdose following Civox administration may lead to seizures, hallucinations, confusion, abdominal discomfort, renal and hepatic impairment as well as crystalluria, haematuria, & reversible renal toxicity

PrecautionsWarnings

Should be used with caution in patients with suspected or known CNS disorders such as arteriosclerosis or epilepsy, and certain dietary precautions should also be observed

PediatricUses

Not a drug of first choice in pediatric population

TherapeuticClass

  • 4-Quinolone preparations
  • Anti-diarrhoeal Antimicrobial drugs

StorageConditions

Keep below 30°C temperature, protected from light & moisture, and keep out of the reach of children

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