Deflox DS 250 mg/5 ml (Powder for Suspension)

60 ml bottle: ৳ 80.00

Medicine Details

Indications

  • Treatment of single infection or mixed infections caused by susceptible organisms
  • Can be used for infections caused by organisms resistant to other antibiotics
  • Treatment of urinary, respiratory, and gastrointestinal tract infections
  • Treatment of skin and soft tissue infections
  • Treatment of gastrointestinal infections
  • Treatment of bone and joint infections
  • Treatment of pelvic infections
  • Treatment of eye, ear, nose, and throat infections
  • Treatment of gonorrhea
  • Treatment of biliary tract infections
  • Treatment of intra-abdominal infections

Pharmacology

  • Broad spectrum of activity
  • Active against gram-negative and gram-positive aerobic bacteria
  • Bactericidal action results from interference with DNA gyrase
  • Well-absorbed from the gastrointestinal tract
  • Widely distributed into body tissues and fluids
  • Half-life of approximately 3.5 hours
  • Excretion in urine
  • Synthetic quinolone anti-infective agent

Dosage

  • Dosage range for adults: 100-750 mg twice daily
  • Specific dosages for urinary, respiratory, and gastrointestinal tract infections
  • Dosage adjustment for impaired renal function
  • Duration of treatment depending on severity of infection
  • Dosage recommendations for adolescents and children
  • Extended-release tablet recommendations
  • IV infusion dosage recommendations

Administration

  • Instructions for IV infusion administration

Interaction

  • Avoid concurrent administration with certain antacids or products containing certain minerals
  • Avoid concurrent intake with milk or dairy products

Contraindications

  • Patients with history of hypersensitivity to the active ingredient or related compounds

Side Effects

  • Gastrointestinal disturbances
  • Disturbances of the central nervous system
  • Hypersensitivity reactions
  • Joint pain
  • Mild photosensitivity
  • Transient increase in liver enzymes
  • Risk of hypoglycemia and mental health adverse effects

Pregnancy & Lactation

  • Not recommended during pregnancy or nursing

Precautions & Warnings

  • Use with caution in patients with suspected or known CNS disorders
  • Caution with concurrent administration of certain products

Use in Special Populations

  • Not a first-choice drug in pediatric population

Overdose Effects

  • Seizures
  • Hallucinations
  • Abdominal discomfort
  • Renal and hepatic impairment
  • Crystalluria
  • Haematuria
  • Reversible renal toxicity

Therapeutic Class

  • 4-Quinolone preparations
  • Anti-diarrhoeal
  • Antimicrobial drugs

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light and moisture
  • Keep out of the reach of children

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