Moxaclav 500 mg+125 mg (Tablet)

Unit Price: ৳ 32.00 (5 x 6: ৳ 960.00)
Strip Price: ৳ 192.00

Medicine Details

Category Details
Generic Amoxicillin clavulanic acid
Company Square pharmaceuticals plc
Also available as
Moxaclav 875 mg tablet Moxaclav 1 gm injection Moxaclav 125 mg suspension Moxaclav 250 mg tablet Moxaclav forte 400 mg suspension

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Genito-urinary tract infections
  • Skin and soft tissue infections
  • Bone and joint infections
  • Surgical prophylaxis

Composition

  • 375 mg tablet
  • 625 mg tablet
  • 1 gm tablet
  • Powder for Suspension
  • Powder for Suspension (Forte)
  • 1.2 gm Injection
  • 0.6 gm injection

Pharmacology

  • Bactericidal activity against Gram-positive microorganisms
  • Bactericidal activity against Gram-negative microorganisms
  • Degradation susceptibility by (3-lactamases
  • Inactivation of beta-lactamase enzymes
  • Amoxicillin spectrum of activity enhancement
  • Clavulanic acid spectrum extension

Dosage

  • Adult dosage
  • Children dosage
  • Recommended daily dosage
  • Serious infection dosage

Administration

  • Oral dosage form
  • IV injection administration
  • Enhanced absorption with meal intake
  • Recommended usage timeframe

Interaction

  • Prolongation of bleeding time
  • Reduced efficacy of oral contraceptives
  • Concomitant use with allopurinol

Contraindications

  • History of Penicillin hypersensitivity
  • Cross-sensitivity with other beta-lactam antibiotics
  • Penicillin-associated cholestatic jaundice

Side Effects

  • Mild and transitory nature
  • Diarrhea
  • Nausea
  • Hepatitis
  • Cholestatic jaundice
  • Angioedema
  • Anaphylaxis

Pregnancy & Lactation

  • No teratogenic effect in animal studies
  • Limited use in human pregnancy
  • Traces in breast milk during lactation

Precautions & Warnings

  • Use with care in patients on anticoagulation therapy
  • Dosage adjustment for renal impairment
  • Maintenance of adequate fluid intake

Use in Special Populations

  • Dose adjustments for renal impairment
  • Monitoring of hepatic function

Overdose Effects

  • Unlikely occurrence
  • Gastrointestinal symptoms
  • Fluid and electrolyte balance disturbance

Therapeutic Class

  • Broad spectrum penicillins

Reconstitution

  • IV injection reconstitution
  • Reconstitution precautions

Storage Conditions

  • Storage temperature
  • Protection from light and moisture
  • Refrigeration after reconstitution

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