Dumaflox 250 mg/5 ml (Powder for Suspension)

60 ml bottle: ৳ 100.00

Medicine Details

Title and Categories

  • Dumaflox 4-Quinolone Anti-infective Agent
  • Anti-diarrhoeal Antimicrobial Drugs

Indications

  • Treatment of single infection or mixed infections
  • Infections caused by susceptible organisms
  • Infections resistant to other antibiotics
  • Wide range of infections in urinary, respiratory, and gastrointestinal tracts
  • Infections in immunosuppressed patients
  • Infections of skin, soft tissue, and biliary tract
  • Management of bone and joint infections
  • Treatment of eye, ear, nose, and throat infections
  • Therapeutic use for gonorrhea

Pharmacology

  • Synthetic quinolone anti-infective agent
  • Broad spectrum activity against gram-negative and gram-positive aerobic bacteria
  • Bactericidal action by interference with DNA gyrase enzyme
  • Rapid and well absorption from gastrointestinal tract
  • Widely distributed into body tissues and fluids
  • Excretion in urine as unchanged drug and active metabolites

Dosage

  • Dosage determined by severity, type of infection, and patient characteristics
  • Dosage range for adults: 100-750 mg twice daily
  • Specific dosage recommendations for different infections

Administration

  • Instruction for the use of Ciprofloxacin IV infusion
  • Guidelines for checking solution integrity and proper administration set-up

Interaction

  • Avoid concurrent administration with certain antacids and dairy products
  • Recommendations for timing of other product intake relative to Dumaflox
  • Impact of dietary calcium on Dumaflox absorption

Contraindications

  • History of hypersensitivity to Ciprofloxacin or other quinolones

Side Effects

  • Gastrointestinal disturbances
  • Central nervous system disturbances
  • Hypersensitivity reactions
  • Joint pain, photosensitivity, transient increase in liver enzymes
  • Risk of hypoglycemia and mental health adverse effects

Pregnancy & Lactation

  • Reproduction studies showing no evidence of teratogenicity
  • Risk of causing arthropathy in immature animals
  • Not recommended for use during pregnancy and nursing mothers

Precautions & Warnings

  • Caution in patients with CNS disorders
  • Guidance on administration with or without meals and fluid intake
  • Avoid concurrent administration with specific products
  • Impact of dietary calcium on Dumaflox absorption

Use in Special Populations

  • Effective in clinical trials but not a first choice in pediatric population

Overdose Effects

  • Potential effects on seizures, hallucinations, renal and hepatic impairment

Therapeutic Class

  • 4-Quinolone preparations
  • Anti-diarrhoeal Antimicrobial drugs

Storage Conditions

  • Keep below 30°C temperature
  • Protection from light and moisture
  • Keep out of the reach of children

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