G-Cipro 500 mg (Tablet)

Title

• G-Cipro

Categories

• Antibacterial
• Anti-infective
• Medication

Description

• Treatment for single and mixed infections
• Broad spectrum of activity against various bacteria
• Effective in infections of urinary, respiratory, and gastrointestinal tracts
• Can be used in gonorrhea and septicaemia
• Intravenous and oral administration options

Brand

• G-Cipro

DosageForm

• Tablet
• Extended-release tablet
• IV infusion

ActiveIngredient

• Ciprofloxacin

SpectrumOfActivity

• Gram-negative aerobic bacteria
• Enterobacteriaceae
• Pseudomonas aeruginosa
• Gram-positive aerobic bacteria
• Penicillinase producing bacteria
• Methicillin resistant staphylococci

RouteOfAdministration

• Oral
• Intravenous

DosageRange

• 100-750 mg twice daily for adults
• 250-500 mg twice daily for urinary tract infections
• 250-500mg twice daily for respiratory tract infections
• 750 mg twice daily for Streptococcus pneumonia infection

Warnings

• Use with caution in patients with CNS disorders
• Avoid concurrent use with magnesium/aluminium antacids
• Not recommended for use with milk or dairy products

StorageConditions

• Store below 30°C
• Protect from light and moisture
• Keep out of reach of children

PregnancyAndLactation

• Not recommended during pregnancy due to potential arthropathy in animals
• Not recommended for nursing mothers

Contraindications

• Hypersensitivity to Ciprofloxacin or quinolones

SideEffects

• Gastrointestinal disturbances
• Central nervous system disturbances
• Hypersensitivity reactions
• Joint pain
• Photosensitivity
• Increased liver enzymes

SpecialPopulations

• Not first choice in pediatric population

Indications

• Treatment of severe systemic infections
• Respiratory tract infections
• Urinary tract infections
• Skin and soft tissue infections
• Gastrointestinal infections

Pharmacology

• Inhibition of DNA gyrase for bacterial DNA synthesis

Interactions

• Avoid concurrent use with certain antacids and dairy products

OverdoseEffects

• Seizures
• Hallucinations
• Renal and hepatic impairment

DrugClasses

• 4-Quinolone preparations
• Anti-diarrhoeal Antimicrobial drugs

DurationOfTreatment

• 5-10 days for acute infections

ModeOfAction

• Inhibition of DNA gyrase

Usability

• Effective for infections resistant to other antibiotics

Compatibility

• Compatible with Aminoglycosides and beta lactam antibiotics

AgeGroup

• Dosage adjustment in patients with impaired renal function
• Caution in elderly patients

BodyTissues

• Reached by antibacterial concentrations

Distribution

• Widely distributed into body tissues and fluids

Excretion

• 30-50% excreted in urine within 24 hours

HalfLife

• Approximately 3.5 hours

DietaryConsiderations

• Absorption not affected by dietary calcium as part of meal

DosageAdjustment

• Required in patients with severe renal impairment

AdverseEffects

• Possible systemic reactions
• Risk of retinal detachment

ImmuneResponse

• Possible skin rash and pruritus

Metabolism

• Biologically active metabolites

Arthropathy

• Caution in use with children and growing adolescents

ClinicalResponse

• Treatment should be continued for 3 days after infection signs disappear

Precautions

• Fluid intake encouraged
• Do not use if solution is cloudy or has a precipitate

SeverityOfInfection

• Dosage determined by severity
• Treatment duration based on clinical response

Efficacy

• Effective against resistant organisms

Related Brands

• G-Cipro 200 mg/100 ml (IV Infusion) - gonoshasthaya-pharma-ltd
• Geflox 250 mg (Tablet) - general-pharmaceuticals-ltd
• Geflox 500 mg (Tablet) - general-pharmaceuticals-ltd
• Geflox 250 mg/5 ml (Powder for Suspension) - general-pharmaceuticals-ltd
• Geflox 200 mg/100 ml (IV Infusion) - general-pharmaceuticals-ltd