Geflox 500 mg (Tablet)
Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)
Strip Price: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ciprofloxacin |
| Company | General pharmaceuticals ltd |
| Also available as |
Title and Category
- Geflox Medicine
- Anti-infective Agent
Type
- Tablets
- IV Infusion
Dosage Range
- 100-750 mg twice daily for adults
- 250-500 mg twice daily for urinary tract infections
- 250-500 mg twice daily for respiratory tract infections
- 500-750 mg twice daily for most other infections
- 750 mg twice daily for cystic fibrosis
Dosage for Specific Conditions
- Single dose of 250 or 500 mg for gonorrhea
- 7.5-15 mg/kg/day for children
- 1000 mg extended-release tablet once daily for uncomplicated urinary tract infection
Administration Instructions
- IV infusion setup instructions
Pharmacology
- Synthetic quinolone anti-infective agent
- Broad spectrum of activity against various bacteria
- Mechanism of action involving interference with DNA gyrase
Indications
- Treatment of severe systemic infections
- Urinary tract infections
- Respiratory tract infections
- Skin and soft tissue infections
- Gastrointestinal infections
- Infections of biliary tract
- Bone and joint infections
- Eye, ear, nose, and throat infections
- Gonorrhea
- Pelvic infections
- Intra-abdominal infections
Interaction
- Avoid concurrent administration with certain antacids and dairy products
Contraindications
- Hypersensitivity to Ciprofloxacin or other quinolones
Side Effects
- Gastrointestinal disturbances
- Central nervous system disturbances
- Hypersensitivity reactions
- Joint pain
- Mild photosensitivity
- Transient increase in liver enzymes
Pregnancy & Lactation
- Not recommended for use during pregnancy due to arthropathy in immature animals
- Not recommended for nursing mothers
Precautions & Warnings
- Use with caution in patients with CNS disorders or predisposition to seizures
- Avoid concurrent use with specific products
Use in Special Populations
- Not a drug of first choice in pediatric population
Overdose Effects
- Seizures
- Hallucinations
- Abdominal discomfort
- Renal and hepatic impairment
- Crystalluria
- Haematuria
- Reversible renal toxicity
Therapeutic Class
- 4-Quinolone preparations
- Anti-diarrhoeal Antimicrobial drugs
Storage Conditions
- Keep below 30°C
- Protected from light and moisture
- Keep out of the reach of children
Absorption and Excretion
- Rapid and well-absorbed from the G.I. tract
- Widely distributed into body tissues and fluids
- About 30-50% excreted in urine within 24 hours
Duration of Treatment
- Depends upon severity of infection, clinical response, and bacteriological findings
Impaired Renal Function
- Adjustment may be necessary in patients with severe renal impairment
Elderly Usage
- No dosage adjustment necessary despite higher serum levels
Studies
- No evidence of teratogenicity, impairment of fertility, or impairment of peri/postnatal development in reproduction studies
Pediatric Usage
- Effective in clinical trials but not a first choice drug