Hiflox 750 mg (Tablet)
Unit Price: ৳ 12.05 (20's pack: ৳ 241.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ciprofloxacin |
| Company | Ambee pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of single and mixed infections
- Antibacterial activity for a wide range of infections
- Treatment of urinary, respiratory, and gastrointestinal tract infections
- Treatment of gonorrhea and septicaemia
- Treatment of skin, soft tissue, and gastrointestinal infections
- Treatment of bone and joint infections
- Usability for eye, ear, nose, and throat infections
- Use in patients with haematological or solid tumors
- Treatment of biliary tract infections
- Use in intensive care unit patients with specific problems
Pharmacology
- Synthetic quinolone anti-infective agent
- Broad spectrum of activity against gram-negative and gram-positive bacteria
- Bactericidal action via interference with DNA gyrase
- Rapid and well absorption from the gastrointestinal tract
- Widely distributed into body tissues and fluids
- Excretion of unchanged drug and biologically active metabolites in urine
Dosage
- Dosage determined by infection severity, causative organism sensitivity, and patient age/renal function
- Dosage range for adults: 100-750 mg twice daily
- Specific dosages for different types of infections
- Duration of treatment based on severity and clinical response
- Special dosage considerations for impaired renal function, elderly, adolescents, and children
Administration
- Instruction for use of Ciprofloxacin IV infusion
- Guidelines for checking IV bag for leaks and cloudiness
- Regulation of infusion rate with flow control clamp
Interaction
- Avoid concurrent administration with magnesium or aluminum containing antacids
- Avoid concurrent administration with products containing calcium, iron, or zinc
- Precautions against concurrent intake with milk or dairy products
Contraindications
- History of hypersensitivity to Ciprofloxacin or other quinolones
Side Effects
- Gastrointestinal disturbances such as nausea, diarrhea, vomiting
- Central nervous system disturbances like headache, dizziness, tiredness
- Hypersensitivity reactions including skin rash and pruritus
- Joint pain, mild photosensitivity, and transient increase in liver enzymes reported
Pregnancy & Lactation
- No evidence of teratogenicity, fertility impairment, or peri/postnatal development impairment in reproduction studies
- Not recommended for use during pregnancy due to potential arthropathy in immature animals
- Secretion in milk indicates not recommended for nursing mothers
Precautions & Warnings
- Use with caution in patients with CNS disorders or factors predisposing to seizures
- Instructions for use with or without meals and liberal fluid intake
- Precautions against concurrent intake with certain antacids or dairy products
Use in Special Populations
- Effective in clinical trials but not a first choice in pediatric population
Overdose Effects
- May lead to seizures, hallucinations, confusion, abdominal discomfort
- Risk of renal and hepatic impairment, crystalluria, and haematuria
Therapeutic Class
- 4-Quinolone preparations
- Anti-diarrhoeal antimicrobial drugs
Storage Conditions
- Keep below 30°C temperature
- Protected from light and moisture
- Keep out of the reach of children